Skip to main content
SpringerLink
Log in

Chiral Separation of 4-Iminoflavan Derivatives on Several Polysaccharide-Based Chiral Stationary Phases by HPLC

  • Original
  • Published:
Chromatographia Aims and scope Submit manuscript

An Erratum to this article was published on 16 September 2014

Abstract

The HPLC enantiomeric separation of seven 4-iminoflavans was successfully accomplished in the normal phase mode using six polysaccharide-based chiral stationary phases namely, Chiralcel®OD-H, Chiralcel®OD, Chiralcel®OJ, Chiralpak®AD, Chiralpak®IA and Chiralpak®IB under normal and polar organic phase modes. The resolution depended on nature and concentration of alcoholic modifier. The results demonstrate clearly that the chromatographic system based on the coated and immobilized type Chiralpak®IB and Chiralcel®OD-H CSPs provide a powerful analytical tool for enantiomeric separation of all the 4-iminoflavans used in this study.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Collins MJ, Waite ER, van Duin ACT (1999) Philos Trans R Soc Lond B 354:51–64

    Article  CAS  Google Scholar 

  2. Asztemborska M, Zukowski JJ (2006) Chromatogr A 1134:95–100

    Article  CAS  Google Scholar 

  3. Trapp O, Schoetz G, Schurig V (2001) Chirality 13:403–414

    Article  CAS  Google Scholar 

  4. Reich S, Trapp O, Schurig V (2000) J Chromatogr A 892:487–498

    Article  CAS  Google Scholar 

  5. Krupcik J, Oswald P, Majek P, Sandra P, Armstrong DW (2003) J Chromatogr A 100:779–800

    Article  Google Scholar 

  6. Wolf C (2005) Chem Soc Rev 34:595–608

    Article  CAS  Google Scholar 

  7. Yáñez JA, Andrews PK, Davies NM (2007) J Chromatogr B 848:159–181

    Article  Google Scholar 

  8. Marin F, Perez-Alvarez FJ, Martinez-Sanchez F (2002) Del Rio J Stud Nat Prod Chem 26:747–778

    Google Scholar 

  9. Cirilli R, Ferretti R, De Santis E, Gallinella B, Zanitti L, La Torre F (2008) J Chromatogr A 1190:95–101

    Article  CAS  Google Scholar 

  10. Lahmer N, Belboukhari N, Cheriti A (2011) Phyto Chem Bio Sub J 5:1–4

    Google Scholar 

  11. Belboukhari N, Rahou I, Cheriti A, Benmiloud A, Cheikh N, Gouma OF (2011) Phyto Chem Biol Sub J 5:170–173

    Google Scholar 

  12. Lahmar N, Belboukhari N, Cheriti A (2013) Int J Chem Stud 1:1–5

    Google Scholar 

  13. Aitmambetov A, Kubzheterova A (2002) Russian J Bioorg Chem 28:189–190

    Article  CAS  Google Scholar 

  14. Maltese F, Erkelens C, van der Kooy F, Choi YC, Verpoorte R (2009) Food Chem 116:575–579

    Article  CAS  Google Scholar 

  15. Caccamese S, Manna L, Scivoli G (2003) Chirality 15:661–667

    Article  CAS  Google Scholar 

  16. Patil SG, Utale P, Gholse SB, Pande SV (2012) J Chem Pharm Res 4:501–507

  17. Belboukhari N, Cheriti A, Roussel C, Vanthuyne N (2010) Nat Prod Res 247:669–681

    Article  Google Scholar 

  18. Belboukhari N (2012) J Chromat Separation Techniq 3:67–68

    Google Scholar 

  19. Lahmer N, Belboukhari N, Cheriti A (2011) Phytochem Biosub J 5:13–18

    Google Scholar 

  20. Ye YK, Lynam KG, Stringham RW (2006) Chirality 18:1–9

    Article  Google Scholar 

  21. Rudaz S, Veuthey JL (1999) Chirality 11:319–325

    Article  CAS  Google Scholar 

  22. Musharraf SG, Shoaib M, Najam-ul-Haq M (2012) Chem Cent J 6:93–97

    Article  CAS  Google Scholar 

  23. Chilmonczyk Z, Ksycinska H, Mazgajska M, Aboul-Enein HY (1999) Chirality 11:790–742

Download references

Conflict of interest

The authors declare no conflict of interests.

Author information

Authors and Affiliations

  1. Bioactive Molecules and Chiral Separation Laboratory, Faculty of Science and Technology, University of Bechar, Bechar, Algeria

    Ismahan Rahou, Nasser Belboukhari & Khaled Sekkoum

  2. Phytochemistry and Organic Synthesis Laboratory, Faculty of Science and Technology, University of Bechar, Bechar, Algeria

    Abdelkarim Cheriti

  3. Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Center, Dokki, Cairo, Egypt

    Hassan Y. Aboul-Enein

Authors
  1. Ismahan Rahou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Nasser Belboukhari
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Khaled Sekkoum
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Abdelkarim Cheriti
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Hassan Y. Aboul-Enein
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hassan Y. Aboul-Enein.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rahou, I., Belboukhari, N., Sekkoum, K. et al. Chiral Separation of 4-Iminoflavan Derivatives on Several Polysaccharide-Based Chiral Stationary Phases by HPLC. Chromatographia 77, 1195–1201 (2014). https://doi.org/10.1007/s10337-014-2714-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10337-014-2714-9

Keywords

Search

Navigation