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Interpretation of cardiac wall motion from cine-MRI combined with parametric imaging based on the Hilbert transform

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Abstract

Object

The aim of this study was to test and validate the clinical impact of parametric amplitude images obtained using the Hilbert transform on the regional interpretation of cardiac wall motion abnormalities from cine-MR images by non-expert radiologists compared with expert consensus.

Materials and methods

Cine-MRI short-axis images obtained in 20 patients (10 with myocardial infarction, 5 with myocarditis and 5 with normal function) were processed to compute a parametric amplitude image for each using the Hilbert transform. Two expert radiologists blindly reviewed the cine-MR images to define a gold standard for wall motion interpretation for each left ventricular sector. Two non-expert radiologists reviewed and graded the same images without and in combination with parametric images. Grades assigned to each segment in the two separate sessions were compared with the gold standard.

Results

According to expert interpretation, 264/320 (82.5%) segments were classified as normal and 56/320 (17.5%) were considered abnormal. The accuracy of the non-expert radiologists’ grades compared to the gold standard was significantly improved by adding parametric images (from 87.2 to 94.6%) together with sensitivity (from 64.29 to 84.4%) and specificity (from 92 to 96.9%), also resulting in reduced interobserver variability (from 12.8 to 5.6%).

Conclusion

The use of parametric amplitude images based on the Hilbert transform in conjunction with cine-MRI was shown to be a promising technique for improvement of the detection of left ventricular wall motion abnormalities in less expert radiologists.

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Authors’contribution

Benameur performed the analysis, interpreted the data and wrote the manuscript. Caiani contributed to the study design, manuscript preparation and statistical analysis. Arous analyzed data and helped in data interpretation. Ben Abdallah analyzed data and contributed to the data collection. Kraiem supervised the development of the work and helped in the manuscript evaluation.

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Authors and Affiliations

  1. University of Tunis El Manar, Higher Institute of Medical Technologies of Tunis, Laboratory of Biophysics and Medical Technology, Tunis, Tunisia

    Narjes Benameur & Tarek Kraiem

  2. Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy

    Enrico Gianluca Caiani

  3. Military Hospital of Instruction of Tunis, Tunis, Tunisia

    Younes Arous & Nejmeddine ben Abdallah

Authors
  1. Narjes Benameur
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  2. Enrico Gianluca Caiani
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  3. Younes Arous
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  4. Nejmeddine ben Abdallah
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  5. Tarek Kraiem
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Correspondence to Narjes Benameur.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Benameur, N., Caiani, E.G., Arous, Y. et al. Interpretation of cardiac wall motion from cine-MRI combined with parametric imaging based on the Hilbert transform. Magn Reson Mater Phy 30, 347–357 (2017). https://doi.org/10.1007/s10334-017-0609-0

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  • DOI: https://doi.org/10.1007/s10334-017-0609-0

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