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Contaminants in water: non-target UHPLC/MS analysis

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Abstract

Contamination of water resources is one of the major problems to be faced for environment preservation and sustainability. The monitoring of target compounds based on mass spectrometry and selected reaction monitoring mode is often insufficient to definitely assess the quality of surface water. Also potentially harmful non-target pollutants simultaneously present must be taken into account. Liquid chromatography coupled with tandem mass spectrometry is suitable to obtain complete information on water composition. Hybrid mass spectrometers such as triple quadrupole/linear ion trap, hybrid quadrupole/time-of-flight and linear ion trap/orbitrap analyzers should be used. Here, we review ultra-high performance liquid chromatography coupled with mass spectrometry methods developed for post-target and non-target screening analysis of water emerging contaminants, such as pesticides and their degradation products, pharmaceuticals and drug side-reaction products, surfactants and illicit drugs. The major points are the following: (1) the possibility of performing retrospective analysis only by high-resolution mass analyzer; (2) the compatibility of mass analyzer with ultra-high performance liquid chromatography; (3) the use of deconvolution software to detect unknowns; and (4) the limited availability of library database.

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  1. Department of Science and Technological Innovation - DISIT, University of Piemonte Orientale, viale T. Michel 11, 15121, Alessandria, Italy

    Fabio Gosetti, Eleonora Mazzucco, Maria Carla Gennaro & Emilio Marengo

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  1. Fabio Gosetti
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Correspondence to Fabio Gosetti.

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Gosetti, F., Mazzucco, E., Gennaro, M.C. et al. Contaminants in water: non-target UHPLC/MS analysis. Environ Chem Lett 14, 51–65 (2016). https://doi.org/10.1007/s10311-015-0527-1

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