Abstract
We investigated the effects of exercise training on heart rate variability (HRV) and myocardial adrenergic and muscarinic receptors in rats. Exercise training induced a decrease in body mass while ventricular size remained unchanged, a development we considered as a relative cardiac hypertrophy. In addition, there was a reduction in the density of myocardial β1-adrenergic receptors. These structural changes were associated with functional adaptations, as illustrated by the increased response of the sinus node to sympathetic blockade.
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* Drs. Barbier and Reland contributed equally to this work
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Barbier*, J., Reland*, S., Ville, N. et al. The effects of exercise training on myocardial adrenergic and muscarinic receptors. Clin Auton Res 16, 61–65 (2006). https://doi.org/10.1007/s10286-006-0312-0
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DOI: https://doi.org/10.1007/s10286-006-0312-0