Original Article

Amino Acids

, Volume 40, Issue 3, pp 975-980

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

PROlocalizer: integrated web service for protein subcellular localization prediction

  • Kirsti LaurilaAffiliated withDepartment of Signal Processing, Tampere University of TechnologyInstitute of Medical Technology, University of Tampere
  • , Mauno VihinenAffiliated withInstitute of Medical Technology, University of TampereScience Center, Tampere University Hospital Email author 


Subcellular localization is an important protein property, which is related to function, interactions and other features. As experimental determination of the localization can be tedious, especially for large numbers of proteins, a number of prediction tools have been developed. We developed the PROlocalizer service that integrates 11 individual methods to predict altogether 12 localizations for animal proteins. The method allows the submission of a number of proteins and mutations and generates a detailed informative document of the prediction and obtained results. PROlocalizer is available at http://​bioinf.​uta.​fi/​PROlocalizer/​.


Protein localization prediction Cell compartments Mutations Disease-causing mutations Prediction method