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Highly chemiluminescent metal-organic framework of type MIL-101(Cr) for detection of hydrogen peroxide and pyrophosphate ions

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Abstract

The authors describe a highly chemiluminescent metal-organic framework (MOF) that was obtained by loading the pores of MIL-101(Cr) with luminol. Immobilization is based on Lewis acid-base interactions between the coordinatively unsaturated metal sites of MIL-101(Cr) and the amino groups of luminol. The luminol-loaded MOF displays strong chemiluminescence (CL) in the presence of hydrogen peroxide (H2O2) in alkaline solution. Pyrophosphate (PPi), in turn, acts as a quencher of this CL. These findings have been exploited in the design of a CL based method for the determination of either H2O2 or PPi. The assays for H2O2 works in the 3 to 100 μM concentration range and has a detection limit of 0.5 μM. The quenchometric assay for PPi works in the 5 to 70 μM concentration range and has a 1.2 μM detection limit.

Luminol-embedded metal-organic frameworks (MOFs) with high chemiluminescent activity were prepared and used for the sensitive determination of either H2O2 or pyrophosphate ions.

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Acknowledgments

We thank the financial support from the Doctoral Program of Southwest University of Science and Technology (Grant No. 14zx7165) and Teaching Reform Project of Southwest University of Science and Technology (Grant No. 16xn0022).

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Authors and Affiliations

  1. School of National Defence Science & Technology, Southwest University of Science and Technology, Mianyang, Sichuan, 621010, People’s Republic of China

    Haili Yu & Dengying Long

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  1. Haili Yu
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  2. Dengying Long
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Correspondence to Haili Yu.

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Yu, H., Long, D. Highly chemiluminescent metal-organic framework of type MIL-101(Cr) for detection of hydrogen peroxide and pyrophosphate ions. Microchim Acta 183, 3151–3157 (2016). https://doi.org/10.1007/s00604-016-1963-8

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  • DOI: https://doi.org/10.1007/s00604-016-1963-8

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