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Development of protocol for the management of cervical cancer symptoms in resource-constrained developing countries

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Abstract

Cervical cancer is the commonest malignancy of women in economically emerging countries. Patients have distressing symptoms from presentation through follow-up or end of life. Cervical cancer imposes significant burden on health care system due to distressing symptoms and associated loss of quality-adjusted life years (QALY). Multitude of drugs and surgical measures in various combinations can relieve these distressing symptoms and various clinical conditions. The protocols and guidelines for alleviation or relief of symptoms by general pharmacological and surgical measures form an important policy subject in planning cervical cancer management program. These protocol and guidelines are based on the mechanism of action of drugs, extrapolation from management of similar symptoms, and clinical situations arising out of other non-cancerous conditions and experience of health care professionals. Therefore, rigorous evaluation of effectiveness of supportive health care services in developing countries is the need of hour. However, evaluation of such protocol and guidelines are not feasible in emerging economies due to resource constraint. Industrialized affluent nations are also not able to implement and further support care guidelines despite its recognition as an integral part of multidisciplinary management of cancer. Aforementioned factors have created blind spot zone of management purview of cervical cancer. Hence, we attempt to develop protocol for management of adverse events of cervical cancer. Symptoms’ and medical conditions’ management guidelines evolved on the basis of empirical clinical practice in community and premier oncology centers in resource-constrained developing countries has been presented in this short report. This report should not be an end in itself but has to attract attention of policy-makers, academicians, researchers, and practitioners toward advancing supportive care needs of cancer patients in low- and middle-income countries (LMIC).

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References

  1. Long HJ, Laack NN, Gostout BS (2007) Prevention, diagnosis, and treatment of cervical cancer. Mayo Clin Proc 82(12):1566–74

    Article  PubMed  Google Scholar 

  2. Pasek M, Suchocka L, Urbański K (2013) Quality of life in cervical cancer patients treated with radiation therapy. J Clin Nurs 22(5–6):690–7

    PubMed  Google Scholar 

  3. Stone HB, Coleman CN, Anscher MS, McBride WH (2003) Effects of radiation on normal tissue: consequences and mechanisms. Lancet Oncol 4(9):529–36

    Article  CAS  PubMed  Google Scholar 

  4. Baze C, Monk BJ, Herzog TJ (2008) The impact of cervical cancer on quality of life: a personal account. Gynecol Oncol 109(2 Suppl):S12–4

    Article  PubMed  Google Scholar 

  5. Cancer Therapy Evaluation Program: NCI Common Terminology Criteria for AE(CTCAE v4.0). Book NCI Common Terminology Criteria for AE(CTCAE v4.0) 2006

  6. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61(2):69–90, Mar-Apr

    Article  PubMed  Google Scholar 

  7. Aapro M, Andre F, Blackwell K, Calvo E, Jahanzeb M, Papazisis K et al (2014) Adverse event management in patients with advanced cancer receiving oral everolimus: focus on breast cancer. Ann Oncol 25(4):763–73

    Article  CAS  PubMed  Google Scholar 

  8. Peterson ME (2013) Management of adverse events in patients with hormone receptor-positive breast cancer treated with everolimus: observations from a phase III clinical trial. Support Care Cancer 21(8):2341–2349

    Article  PubMed Central  PubMed  Google Scholar 

  9. Scotté F (2012) The importance of supportive care in optimizing treatment outcomes of patients with advanced prostate cancer. Oncologist 17(Suppl 1):23–30

    Article  PubMed Central  PubMed  Google Scholar 

  10. Urban C, Benesch M, Lackner H, Schwinger W, Kerbl R, Gadner H (1997) The influence of maximum supportive care on dose compliance and survival. Single-center analysis of childhood acute lymphoblastic leukemia and non-Hodgkin’s-lymphoma treated within 1984–1993. Klin Padiatr 209(4):235–42, Jul-Aug

    Article  CAS  PubMed  Google Scholar 

  11. Kreys ED, Kim TY, Delgado A, Koeller JM (2014) Impact of cancer supportive care pathways compliance on emergency department visits and hospitalizations. J Oncol Pract 10(3):168–73

    Article  PubMed  Google Scholar 

  12. Burke J. Census reveals that 17 % of the world is Indian. The guardian [Internet]. 2011 Mar 31. http://www.theguardian.com/world/2011/mar/31/census-17-percent-world-indian. Accessed 4 Aug 2014

  13. Murthy NS, Chaudhry K, Rath GK (2008) Burden of cancer and projections for 2016, Indian scenario: gaps in the availability of radiotherapy treatment facilities. Asian Pac J Cancer Prev 9(4):671–7, Oct-Dec

    CAS  PubMed  Google Scholar 

  14. Vanderbilt-Ingram Cancer Center [Internet]. Nashville: Vanderbilt University Medical Center; 2014. http://www.vicc.org/clinics/support/research.php. Accessed 4 Aug 2014

  15. Thadhani R (2006) Chapter 14 - Formal trials versus observational studies. In: Mehta A, Beck M, Sunder-Plassmann G, (eds) Fabry Disease: perspectives from 5 Years of FOS. Oxford, Oxford PharmaGenesis. http://www.ncbi.nlm.nih.gov/books/NBK11597/. Accessed 12 Sept 2014

  16. Park K (2005) Parks’ textbook of preventive and social medicine, 21st edn. Banarsidas Bhanot, Jabalpur (India)

    Google Scholar 

  17. Clay RA (2010) More than one way to measure. Monit Psychol 41(8):52

    Google Scholar 

  18. Wendler D, Emanuel EJ, Lie RK (2004) The standard of care debate: can research in developing countries be both ethical and responsive to those countries’ health needs? Am J Public Health 94(6):923–8

    Article  PubMed Central  PubMed  Google Scholar 

  19. Kumar RV, Bhasker S (2011) Kyoto Breast Cancer Consensus Conference International Convention [Internet]. Kyoto: Kyoto Breast Cancer Consensus Conference; 2014. https://www.kyoto-breast-cancer.org/international/2011/poster.php. Accessed 4 Aug 2014

  20. Hack TF, Carlson L, Butler L, Degner LF, Jakulj F, Pickles T et al (2011) Facilitating the implementation of empirically valid interventions in psychosocial oncology and supportive care. Support Care Cancer 19(8):1097–105

    Article  PubMed  Google Scholar 

  21. Kane RL, Maciejewski M, Finch M (1997) The relationship of patient satisfaction with care and clinical outcomes. Med Care 35(7):714–30

    Article  CAS  PubMed  Google Scholar 

  22. Zolnierek KB, Dimatteo MR (2009) Physician communication and patient adherence to treatment: a meta-analysis. Med Care 47:826–834

    Article  PubMed  Google Scholar 

  23. Doyle C, Lennox L, Bell D (2013) A systematic review of evidence on the links between patient experience and clinical safety and effectiveness. BMJ Open 3:e001570

    Article  PubMed Central  PubMed  Google Scholar 

  24. Hojat M, Louis DZ, Markham FW et al (2011) Physicians’ empathy and clinical outcomes for diabetic patients. Acad Med 86:359–364

    Article  PubMed  Google Scholar 

  25. Ratanawongsa N, Karter AJ, Parker MM et al (2013) Communication and medication refill adherence: the diabetes study of Northern California. JAMA Intern Med 173:210–218

    Article  PubMed Central  PubMed  Google Scholar 

  26. Bhojani U, Mishra A, Amruthavalli S, Devadasan N, Kolsteren P, De Henauw S et al (2013) Constraints faced by urban poor in managing diabetes care: patients’ perspectives from South India. Glob Health Action 6:22258

    PubMed  Google Scholar 

  27. Thompson C, Cullum N, McCaughan D, Sheldon T, Raynor P (2004) Nurses, information use, and clinical decision making—the real world potential for evidence-based decisions in nursing. Evid Based Nurs 7(3):68–72

    Article  PubMed  Google Scholar 

  28. Tripathi KD (2008) Essentials of medical pharmacology, 6th edn. Jaypee Brothers, New Delhi (India)

    Book  Google Scholar 

  29. Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J (2012) Harrison’s principles of internal medicine, 18th edn. McGraw-Hills, New York

    Google Scholar 

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None. We have full control of all primary data, and we are ready to allow the journal to review their data if requested.

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Correspondence to Ramaiah Vinay Kumar.

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Kumar, R.V., Bhasker, S. Development of protocol for the management of cervical cancer symptoms in resource-constrained developing countries. Support Care Cancer 23, 581–600 (2015). https://doi.org/10.1007/s00520-014-2427-5

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