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The association between thoracic periaortic fat and major adverse cardiovascular events

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Abstract

Aim

The study aimed to examine the association between thoracic periaortic fat tissue volume and the long-term incidence of major adverse cardiovascular events.

Methods

This retrospective cohort study included 433 consecutive patients (372 male and 61 female). Periaortic fat tissue volume was measured via electrocardiogram-gated 64-multidetector computed tomography. The patients were evaluated on an average 3 years of follow-up for major adverse cardiovascular events. The patients were divided into groups according to the presence of major adverse cardiovascular events.

Results

Major adverse cardiovascular events were noted in 44 (10.2 %) patients during follow-up. Periaortic fat tissue volume was significantly higher in the major adverse cardiovascular events (+) group (35.4 ± 26.1 cm3 vs. 24.1 ± 14.9 cm3, P = 0.001). The logistic regression model showed that periaortic fat tissue volume (hazard ratio: 1.03; 95 % CI: 1.01–1.05; P = 0.001), the glomerular filtration rate (hazard ratio: 0.98; 95 % CI: 0.96–0.99; P = 0.03), and male gender (hazard ratio: 4.76; 95 % CI: 1.08–20.90; P = 0.04) were independent predictors of major adverse cardiovascular events.

Conclusion

Thoracic periaortic fat tissue volume may be considered a useful new parameter for predicting major adverse cardiovascular events.

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Authors and Affiliations

  1. Department of Cardiology, Mevlana University, Yeni İstanbul Cad. No: 235, 42003, Selçuklu, Konya, Turkey

    Zeynettin Kaya MD,  Seref Ulucan,  Huseyin Katlandur,  Ahmet Keser,  Huseyin Ozdil &  Mehmet S. Ulgen

  2. Department of Cardiology, Necmettin Erbakan University, Konya, Turkey

    MehmetKayrak

  3. Department of Internal Medicine, Mevlana University, Konya, Turkey

    Omer Akyurek

  4. Department of Radiology, Mevlana University, Konya, Turkey

    Duran Efe

Authors
  1. Zeynettin Kaya MD
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  2. Seref Ulucan
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Correspondence to Zeynettin Kaya MD.

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Kaya, Z., Ulucan, S., MehmetKayrak et al. The association between thoracic periaortic fat and major adverse cardiovascular events. Wien Klin Wochenschr 127, 191–196 (2015). https://doi.org/10.1007/s00508-015-0722-x

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  • DOI: https://doi.org/10.1007/s00508-015-0722-x

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