Abstract
Purpose
To analyze the binocular function changes produced on subjects undergoing overnight orthokeratology (OK) treatment over short-term (3 months) and long-term (3 years) wear.
Methods
A prospective, longitudinal study on young adult subjects with low to moderate myopia was carried out. Binocular function was assessed by the following sequence of tests: Distance and near horizontal phoria (Von Graefe technique), distance and near horizontal vergence ranges (Risley rotary prisms), accommodative convergence/accommodation (AC/A) ratio (gradient method) and the near point of convergence (standard push-up technique). The short-term sample consisted of: 21 subjects in the control group, 26 in a corneal refractive therapy (CRT) treatment lenses group and 25 in a Seefree treatment lenses group. Those subjects were evaluated at baseline and at a 3-month follow-up visit. Twenty one subjects were old CRT wearers that attended a 3-year follow-up visit (long-term group).
Results
A statistically significant difference over the 3-month treatment was found for divergence at distance: the break point decreased 1.4 Δ (p = 0.0006) in the CRT group and the recovery point increased 1.2 Δ (p = 0.001) in the Seefree group. Also, the Seefree group had an exophoric trend of 2.3 Δ at near (p = 0.02) and a base-out break decrease of 2.3 Δ (p = 0.03). For the long-term group, only the base-out break point at distant vision showed a statistically significant difference of 4.9 Δ (p = 0.02).
Conclusions
OK induces minimal changes in the binocular function for either short-term or long-term periods, apart from a near exophoric trend over the short-term period.
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References
Jimenez R, Martinez-Almeida L, Salas C, Ortiz C (2011) Contact lenses vs spectacles in myopes: is there any difference in accommodative and binocular function? Graefes Arch Clin Exp Ophthalmol 249(6):925–935. doi:10.1007/s00417-010-1570-z
Fulk GW, Cyert LA, Parker DE, West RW (2003) The effect of changing from glasses to soft contact lenses on myopia progression in adolescents. Ophthalmic Physiol Opt 23(1):71–77. doi:10.1046/j.1475-1313.2003.00094.x
Godts D, Tassignon MJ, Gobin L (2004) Binocular vision impairment after refractive surgery. J Cataract Refract Surg 30(1):101–109. doi:10.1016/s0886-3350(03)00412-7
Godts D, Trau R, Tassignon MJ (2006) Effect of refractive surgery on binocular vision and ocular alignment in patients with manifest or intermittent strabismus. Br J Ophthalmol 90(11):1410–1413. doi:10.1136/bjo.2006.090902
Rued TC, Brungardt TF (1984) Exotropia and orthokeratology: a case report. J Am Optom Assoc 55(1):30–42
McLeod ADL (2006) Effects of overnight orthokeratology on phoria, vergence, and accommodation in children. Thesis (M S), New England College of Optometry
Brand P (2013) The effect of orthokeratology on accommodative and convergence function: a clinic based pilot study. Optom Vis Perform 1(5):162–167
Nieto-Bona A, Gonzalez-Mesa A, Nieto-Bona MP, Villa-Collar C, Lorente-Velazquez A (2011) Short-term effects of overnight orthokeratology on corneal cell morphology and corneal thickness. Cornea 30(6):646–654. doi:10.1097/ICO.0b013e31820009bc
Palomo-Alvarez C, Puell MC (2010) Binocular function in school children with reading difficulties. Graefes Arch Clin Exp Ophthalmol 248(6):885–892. doi:10.1007/s00417-009-1251-y
Rosenfield M, Ciuffreda KJ, Ong E, Super S (1995) Vergence adaptation and the order of clinical vergence range testing. Optom Vis Sci Off Publ Am Acad Optom 72(4):219–223
Downie LE, Lowe R (2013) Corneal Reshaping Influences Myopic Prescription Stability (CRIMPS): an analysis of the effect of orthokeratology on childhood myopic refractive stability. Eye Contact Lens 39(4):303–310. doi:10.1097/ICL.0b013e318298ee76
Hiraoka T, Okamoto C, Ishii Y, Kakita T, Okamoto F, Oshika T (2008) Time course of changes in ocular higher-order aberrations and contrast sensitivity after overnight orthokeratology. Invest Ophthalmol Vis Sci 49(10):4314–4320. doi:10.1167/iovs.07-1586
Gifford P, Li M, Lu H, Miu J, Panjaya M, Swarbrick HA (2013) Corneal versus ocular aberrations after overnight orthokeratology. Optom Vis Sci 90(5):439–447. doi:10.1097/OPX.0b013e31828ec594
González-Mesa A, Villa-Collar C, Lorente-Velázquez A, Nieto-Bona A (2013) Anterior segment changes produced in response to long-term overnight orthokeratology. Curr Eye Res 1–9. doi:10.3109/02713683.2013.790977
Swarbrick HA (2006) Orthokeratology review and update. Clin Exp Optom J Aust Optom Assoc 89(3):124–143. doi:10.1111/j.1444-0938.2006.00044.x
Campbell E (2013) Orthokeratology: an update. Optom Vis Perform 1(1):11–18
Scheiman MM, Wick B (2008) Clinical management of binocular vision : heterophoric, accommodative and eye movement disorders. In: 617.758.1. 3rd edn. Lippincott Williams & Wilkins, Philadelphia
Sreenivasan V, Irving EL, Bobier WR (2008) Binocular adaptation to near addition lenses in emmetropic adults. Vision Res 48(10):1262–1269. doi:10.1016/j.visres.2008.02.015
Goss D, Reynolds J, Todd R (2010) Comparison of four dissociated phoria tets: reliability & correlation with symptom survey scores. J Behav Optom 21(4):99–104
Sreenivasan V, Irving EL, Bobier WR (2012) Effect of heterophoria type and myopia on accommodative and vergence responses during sustained near activity in children. Vision Res 57:9–17. doi:10.1016/j.visres.2012.01.011
Han J, Hong S, Lee S, Kim JK, Lee HK, Han SH (2014) Changes in fusional vergence amplitudes after laser refractive surgery for moderate myopia. J Cataract Refract Surg 40(10):1670–1675. doi:10.1016/j.jcrs.2014.01.043
Cho P, Cheung SW, Edwards M (2005) The longitudinal orthokeratology research in children (LORIC) in Hong Kong: a pilot study on refractive changes and myopic control. Curr Eye Res 30(1):71–80. doi:10.1080/02713680590907256
Walline JJ, Jones LA, Sinnott LT (2009) Corneal reshaping and myopia progression. Br J Ophthalmol 93(9):1181–1185. doi:10.1136/bjo.2008.151365
Kakita T, Hiraoka T, Oshika T (2011) Influence of overnight orthokeratology on axial elongation in childhood myopia. Invest Ophthalmol Vis Sci 52(5):2170–2174. doi:10.1167/iovs.10-5485
Hiraoka T, Kakita T, Okamoto F, Takahashi H, Oshika T (2012) Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia: a 5-year follow-up study. Invest Ophthalmol Vis Sci 53(7):3913–3919. doi:10.1167/iovs.11-8453
Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutierrez-Ortega R (2012) Myopia control with orthokeratology contact lenses in spain: refractive and biometric changes. Invest Ophthalmol Vis Sci 53(8):5060–5065. doi:10.1167/iovs.11-8005
Cho P, Cheung S-W (2012) Retardation of Myopia in Orthokeratology (ROMIO) study: a 2-year randomized clinical trial. Invest Ophthalmol Vis Sci 53(11):7077–7085. doi:10.1167/iovs.12-10565
Swarbrick HA, Alharbi A, Lum E, Watt K (2011) Changes in axial length and refractive error during overnight orthokeratology for myopia control. ARVO Annu Meet Abstr Search Program Plann 2011:2837–2837
Goss DA, Wolter KL (1999) Nearpoint phoria changes associated with the cessation of childhood myopia progression. J Am Optom Assoc 70(12):764–768
Jorge J, de Almeida JB, Parafita MA (2008) Binocular vision changes in university students: a 3-year longitudinal study. Optom Vis Sci 85(10):999–1006
Zhu M, Feng H, Zhu J, Qu X (2014) The impact of amplitude of accommodation on controlling the development of myopia in orthokeratology. Zhonghua Yan Ke Za Zhi 50(1):14–19
Ren Q, Yue H, Zhou Q (2016) Effects of orthokeratology lenses on the magnitude of accommodative lag and accommodativeconvergence/accommodation. Zhong Nan Da Xue Xue Bao Yi Xue Ban J Cent S Univ Med Sci 41(2):169–173. doi:10.11817/j.issn.1672-7347.2016.02.009
Felipe-Marquez G, Nombela-Palomo M, Cacho I, Nieto-Bona A (2015) Accommodative changes produced in response to overnight orthokeratology. Graefes Arch Clin Exp Ophthalmol 253(4):619–626. doi:10.1007/s00417-014-2865-2
Acknowledgements
The authors want to thank Interlenco (Madrid, Spain) and Conóptica (Barcelona, Spain) laboratories for their support.
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Felipe-Marquez, G., Nombela-Palomo, M., Palomo-Álvarez, C. et al. Binocular function changes produced in response to overnight orthokeratology. Graefes Arch Clin Exp Ophthalmol 255, 179–188 (2017). https://doi.org/10.1007/s00417-016-3554-0
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DOI: https://doi.org/10.1007/s00417-016-3554-0