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Forensic characteristics and phylogenetic analyses of the Chinese Yi population via 19 X-chromosomal STR loci

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Abstract

The demographic characteristics and genetic polymorphism data of 56 Chinese nationalities or 31 administrative divisions in Chinese mainland have repeatedly been the genetic research hotspots. While most genetic studies focused on some particular Chinese populations based on autosomal or Y-chromosomal genetic markers, the forensic characteristics and phylogenetic analyses of the seventh largest Chinese population (Yi ethnicity) on the X-chromosomal genetic markers are scarce. Here, allele frequencies and forensic statistical parameters for 19 X-chromosomal short tandem repeat loci (DXS7424-DXS101, DXS6789-DXS6809, DXS7423-DXS10134, DXS10103-HPRTB-DXS10101, DXS10159-DXS10162-DXS10164, DXS10148-DXS10135-DXS8378, and DXS7132-DXS10079-DXS10074-DXS10075) of 331 Chinese Yi individuals were obtained. All 19 X-chromosomal short tandem repeat (STR) loci in females were consistent with the Hardy-Weinberg equilibrium test. A total of 214 alleles were identified with the corresponding allele frequencies spanned from 0.0019 to 0.6106. The combined PE, PDF, and PDM were 0.9999999214, 0.9999999999999999999993, and 0.9999999999998, respectively. The high combined MECKrüger, MECKishida, MECDesmarais, and MECDesmarais Duo were achieved as 0.9999999617638, 0.9999999999971, 0.9999999999971, and 0.9999999931538, respectively. The findings suggested that the panel of 19 X-STR loci is highly polymorphic and informative in the Yi ethnic population and can be considered to be a powerful tool in forensic complex kinship identification. Population differentiation analyses among 12 populations indicated that significant differences in genetic structure were observed in between the Yi ethnicity and the Chinese Uyghur as well as Kazakh, and genetic homogeneity existed in similar ethno-origin or geographic origin populations.

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References

  1. Szibor R (2007) X-chromosomal markers: past, present and future. Forensic Sci Int Genet. 1(2):93–99

    Article  PubMed  Google Scholar 

  2. Szibor R, Krawczak M, Hering S, Edelmann J, Kuhlisch E, Krause D (2003) Use of X-linked markers for forensic purposes. Int J Legal Med 117(2):67–74

    CAS  PubMed  Google Scholar 

  3. Liu YS, Meng HT, Mei T, Zhang LP, Chen JG, Zhang YD et al (2017) Genetic diversity and haplotypic structure of Chinese Kazak ethnic group revealed by 19 STRs on the X chromosome. Gene 600:64–69

    Article  CAS  PubMed  Google Scholar 

  4. Guo YX, Chen JG, Wang Y, Yan JW, Chen J, Yao TH et al (2016) Genetic polymorphism analyses of a novel panel of 19 X-STR loci in the Chinese Uygur ethnic minority. Journal of Zhejiang University Science B 17(5):367–374

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Zhang YD, Shen CM, Meng HT, Guo YX, Dong Q, Yang G et al (2016) Allele and haplotype diversity of new multiplex of 19 ChrX-STR loci in Han population from Guanzhong region (China). Electrophoresis 37(12):1669–1675

    Article  CAS  PubMed  Google Scholar 

  6. He GL, Chen PY, Zou X, Chen X, Song F, Yan J, et al (2017) Genetic polymorphism investigation of the Chinese Yi minority using PowerPlex® Y23 STR amplification system. Int J Legal Med

  7. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16(3):1215

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Gusmao L, Butler JM, Carracedo A, Gill P, Kayser M, Mayr WR et al (2006) DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis. Forensic Sci Int 157(2–3):187–197

    Article  CAS  PubMed  Google Scholar 

  9. Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10(3):564–567

    Article  PubMed  Google Scholar 

  10. Zhang S, Zhao S, Zhu R, Li C (2012) Genetic polymorphisms of 12 X-STR for forensic purposes in Shanghai Han population from China. Mol Biol Rep 39(5):5705–5707 English

    Article  CAS  PubMed  Google Scholar 

  11. Lin M, Liu QS, Huang YL, Che M, Li CQ, Liu YB et al (2011) Population genetics investigation of 12 X chromosome short tandem repeats in the She ethic minority in Fujian. China J Fam Plann 19(10):628–631

  12. Zeng XP, Ren Z, Chen JD, Lv DJ, Tong DY, Chen H et al (2011) Genetic polymorphisms of twelve X-chromosomal STR loci in Chinese Han population from Guangdong Province. Forensic Sci Int Genet. 5(4):e114–e116

  13. Liu YJ, Su WM, Yue JT, Shi SX, Guo LH (2013) Genetic polymorphisms of twelve X-chromosomal STR loci in Han population from Henan Province. J Forensic Med 29(4):297–299

  14. Uchigasaki S, Tie J, Takahashi D (2013) Genetic analysis of twelve X-chromosomal STRs in Japanese and Chinese populations. Mol Biol Rep 40(4):3193–3196

  15. Li XN, Zheng JL, Yao J, Ding M, Pang H, Wang BJ (2014) Population data of 12 X-chromosome STR loci in Yanbian Korean samples from China. Forensic Sci Int Genet 13:143–144 English

  16. Wu XJ, Chen CQ, Jia X, Sun HM, Luo SM, Wei WX et al (2014) Genetic polymorphisms of 12 X- STR loci in Guangdong Zhuang population. Forensic Sci Technol 4:23–26

  17. Wu XJ, Sun HM, Jia X, Chen CQ, Luo SM, Yu DY et al (2014) Genetic polymorphisms of 12 X-STR loci in Guangdong Yao population. China J Forensic Med 29(4):365–367

  18. Edelmann J, Hering S, Kuhlisch E, Szibor R (2002) Validation of the STR DXS7424 and the linkage situation on the X-chromosome. Forensic Sci Int 125(2–3):217–222

    Article  CAS  PubMed  Google Scholar 

  19. Szibor R, Hering S, Kuhlisch E, Plate I, Demberger S, Krawczak M et al (2005) Haplotyping of STR cluster DXS6801-DXS6809-DXS6789 on Xq21 provides a powerful tool for kinship testing. Int J Legal Med 119(6):363–369

    Article  PubMed  Google Scholar 

  20. Hundertmark T, Hering S, Edelmann J, Augustin C, Plate I, Szibor R (2008) The STR cluster DXS10148-DXS8378-DXS10135 provides a powerful tool for X-chromosomal haplotyping at Xp22. Int J Legal Med 122(6):489–492

    Article  PubMed  Google Scholar 

  21. Edelmann J, Hering S, Augustin C, Kalis S, Szibor R (2010) Validation of six closely linked STRs located in the chromosome X centromere region. Int J Legal Med 124(1):83–87

    Article  PubMed  Google Scholar 

  22. Samejima M, Nakamura Y, Minaguchi K (2011) Population genetic study of six closely linked groups of X-STRs in a Japanese population. Int J Legal Med 125(6):895–900

    Article  PubMed  Google Scholar 

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Acknowledgements

The study was supported by the Sichuan Science and Technology Support Program (2014SZ0012).

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Authors and Affiliations

  1. Department of Forensic Genetics, West China School of Preclinical and Forensic Medicine, Sichuan University (West China University of Medical Sciences), Chengdu, Sichuan, 610041, China

    GuangLin He, Ye Li, Feng Song, Tianzhen Gao, Miao Liao, Jing Yan & Jin Wu

  2. Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China

    Xing Zou

  3. Department of Forensic Genetics, Institute of Forensic Science, Guangzhou Public Security Bureau, Guangzhou, Guangdong, 510000, China

    Ping Li

  4. Center of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563099, China

    PengYu Chen

  5. Department of Forensic Medicine, Zunyi Medical University, Zunyi, Guizhou, 563099, China

    PengYu Chen

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  1. GuangLin He
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  2. Ye Li
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  3. Xing Zou
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  4. Ping Li
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  5. PengYu Chen
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  6. Feng Song
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  7. Tianzhen Gao
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  8. Miao Liao
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  9. Jing Yan
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  10. Jin Wu
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Corresponding author

Correspondence to Jin Wu.

Ethics declarations

Our study design was subject to approval by the Ethics Committee of the Institute of Forensic Medicine, Sichuan University, China. Informed consents were achieved before sample collection.

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None.

Additional information

GuangLin He and Ye Li contributed equally to these studies.

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He, G., Li, Y., Zou, X. et al. Forensic characteristics and phylogenetic analyses of the Chinese Yi population via 19 X-chromosomal STR loci. Int J Legal Med 131, 1243–1246 (2017). https://doi.org/10.1007/s00414-017-1563-0

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  • DOI: https://doi.org/10.1007/s00414-017-1563-0

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