Dear Colleague,

Thank you for your review [1] and comments regarding our article [2]. Assessment of MPV has been made within 1 h using EDTA tubes. Regarding your question on the body mass index, smoking status, metabolic syndrome and blood cholesterol levels in our series, cases investigated were non-smokers with no reported co-morbidities such as hypercholesterolemia, metabolic syndrome or obesity. Cases with body mass indices >29.9 had already been excluded from the study.

Despite these efforts to have conditions prone to influence platelet morphology and function, we state that it may not be possible to have all parameters under control. Anyway, we hope that our study will pioneer further studies for a beter understanding of physiopathology of unexplained recurrent miscarriage.