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Antenatally diagnosed lung malformations: a plea for long-term outcome studies

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Abstract

There is a wide variation in the management of infants with antenatally diagnosed lung malformations, with many paediatric surgeons and respiratory paediatricians recommending early investigations for all infants and a surgical excision for the majority of lesions, while others favour a conservative management for all asymptomatic infants. The benefits and risks of a surgical intervention have to be compared with the natural history of the untreated malformation and cohort studies from foetal diagnosis to adult life are required to provide the relevant evidence. Careful and repeated surveillance of identified foetuses is essential as recent advances in foetal medicine and surgery have improved the outcomes for the small minority, who are at risk of developing hydrops.

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Acknowledgments

The authors thank Dr Mudher al-Madani, Histopathologist at Evelina London Children’s Hospital for Fig. 1, Prof Neil Sebire, Histopathologist at the Institute for Child Health, London for Figs. 3 and 7 and Dr Jim Carmichael, Paediatric Radiologist at Evelina London Children’s Hospital for Figs. 4, 5 and 6.

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Authors and Affiliations

  1. Department of Paediatric Surgery, Mater Dei Hospital, L-Imsida, Malta

    Muhammad Choudhry

  2. Department of Paediatric Surgery, Evelina Children’s Hospital, London, England

    David Drake

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  1. Muhammad Choudhry
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  2. David Drake
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Correspondence to Muhammad Choudhry.

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Choudhry, M., Drake, D. Antenatally diagnosed lung malformations: a plea for long-term outcome studies. Pediatr Surg Int 31, 439–444 (2015). https://doi.org/10.1007/s00383-014-3654-z

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