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Intra-vesical Prostatic Protrusion (IPP) Can Be Reduced by Prostatic Artery Embolization

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An Erratum to this article was published on 29 December 2015

Abstract

Background

Prostate artery embolization (PAE) is a new approach to improve lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia. PAE results in global reduction of prostate volume (PV). There are no data available on the efficacy of PAE in reducing intra-vesical prostatic protrusion (IPP), an anatomic feature that is clinically related with bladder outlet obstruction and LUTS.

Objective

To assess the results of PAE in patients with significant IPP due to median lobe hyperplasia and to compare the IPSS decrease and IPP change.

Material and Methods

Prospective analysis of 18 consecutive patients with significant IPP (>5 mm) related to median lobe hyperplasia undergoing PAE using 30–500-μm-calibrated trisacryl microspheres. We measured IPP on sagittal T2-weighted images before and 3 months after PAE. IPSS and clinical results were also evaluated at 3 months.

Results

PAE resulted in significant IPP reduction (1.57 cm ± 0.55 before PAE and 1.30 cm ± 0.46 after PAE, p = 0.0005) (Fig. 1) with no complication. IPSS, quality of life (QoL), total prostate-specific antigen (PSA) level, and PV showed significant reduction after PAE, and maximum urinary flow rate (Q max) showed significant increase after PAE. No significant change of International Index of Erectile Function (IIEF) for clinical evaluation after PAE. A significant correlation was found between the IPP change and the IPSS change (r = 0.636, p = 0.0045).

Conclusion

Patients had significant IPP reduction as well as significant symptomatic improvement after PAE, and these improvements were positively correlated.

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Fig. 1

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Authors and Affiliations

  1. Sorbonne Paris-Cité, Université Paris Descartes, Paris, France

    Olivier Pellerin & Marc Sapoval

  2. Inserm (Institut national de la santé et de la recherche médicale), U970, 56 rue Leblanc, 75015, Paris, France

    Olivier Pellerin & Marc Sapoval

  3. Vascular and Oncological Interventional Radiology, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, 20 rue Leblanc, 75015, Paris, France

    Yen-Ting Lin, Grégory Amouyal, Olivier Pellerin, Héléna Pereira, Costantino Del Giudice, Carole Déan & Marc Sapoval

  4. Urology, Assistance Publique Hopitaux de Paris, Hôpital Européen Georges-Pompidou, 20 rue Leblanc, 75015, Paris, France

    Nicolas Thiounn

  5. Department of Radiology, Taichung Veterans General Hospital, No. 1650, Taiwan Boulevard Sect. 4, Taichung City, Taiwan, ROC

    Yen-Ting Lin

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  1. Yen-Ting Lin
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Correspondence to Yen-Ting Lin.

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All procedures performed in this study were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Lin, YT., Amouyal, G., Thiounn, N. et al. Intra-vesical Prostatic Protrusion (IPP) Can Be Reduced by Prostatic Artery Embolization. Cardiovasc Intervent Radiol 39, 690–695 (2016). https://doi.org/10.1007/s00270-015-1235-8

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  • DOI: https://doi.org/10.1007/s00270-015-1235-8

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