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CT features of hepatic metastases from hepatoid adenocarcinoma

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Abdominal Radiology Aims and scope Submit manuscript

Abstract

Purpose

The purpose of this study was to report the imaging presentation of hepatic metastases from hepatoid adenocarcinoma (HAC).

Methods

We retrospectively identified 11 patients (10 men and 1 woman; median age 66) with HAC liver metastasis who underwent contrast-enhanced computed tomography (CT) which included arterial phase and portal venous phase. Two radiologists analyzed the imaging parameters, which included the enhancement pattern on arterial and portal phase images, necrosis, venous thrombi, and overall imaging diagnosis, and arrived at a consensus.

Results

On arterial phase, the liver lesions had global hyper-enhancement (n = 0), heterogeneous hyper-enhancement (63.6%; n = 7/11), peripheral hyper-enhancement (n = 0), iso-enhancement (n = 0/11), or hypo-enhancement (36.4%; n = 4/11). On portal venous phase, homogenous hypo-enhancement (18.2%; n = 2/11) and heterogenous hypo-enhancement (81.8%; n = 9/11) were observed. Venous thromboses occurred in four patients (36.4%; n = 4/11). The overall imaging diagnoses were “HCC-like” in seven patients (63.6%; n = 7/11), “indeterminable” in 1 patient (9.1%; n = 1/11), and “HCC-unlike” in three patients (27.3%; n = 3/11).

Conclusions

The imaging features of HAC liver metastasis were varied. Arterial phase enhancement coupled with venous phase washout (resembling HCC imaging features) was a major finding, but arterial phase hypo-enhancement (distinct from HCC imaging features) was also frequently encountered.

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Author information

Author notes

  1. Min-Yung Chang

    Present address: Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea

  2. Hye Jin Kim

    Present address: Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea

Authors and Affiliations

  1. Department of Radiology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea

    Min-Yung Chang, Hye Jin Kim, Seung Hyun Park, Joon Seok Lim, Mi-Suk Park, Myeong-Jin Kim & Honsoul Kim

  2. Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Republic of Korea

    Min-Yung Chang, Hye Jin Kim, Seung Hyun Park, Joon Seok Lim, Mi-Suk Park, Myeong-Jin Kim & Honsoul Kim

  3. Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea

    Hyunki Kim

  4. New Drug Development Center, Daegu-Gyeongbuk, Medical Innovation Foundation (DGMIF), Daegu, Republic of Korea

    Dong Kyu Choi

Authors
  1. Min-Yung Chang
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Corresponding author

Correspondence to Honsoul Kim.

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Funding

No funding was received for this study.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

A waiver of informed consent was obtained from the institutional review board as this was a retrospective study and all patients underwent CT as part of their clinical work-up.

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Chang, MY., Kim, H.J., Park, S.H. et al. CT features of hepatic metastases from hepatoid adenocarcinoma. Abdom Radiol 42, 2402–2409 (2017). https://doi.org/10.1007/s00261-017-1150-3

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  • DOI: https://doi.org/10.1007/s00261-017-1150-3

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