Skip to main content

Advertisement

Log in

Pancreaticobiliary disorders: comparison between magnetic resonance cholangiopancreatography images before and after fentanyl injection

  • Published:
Abdominal Imaging Aims and scope Submit manuscript

Abstract

Objective

This study was designed to determine the effects of intravenous fentanyl on magnetic resonance cholangiopancreatography image quality in the treatment of pancreaticobiliary disorders.

Materials and methods

Forty consecutive patients referred for the evaluation of pancreaticobiliary disorders underwent magnetic resonance cholangiopancreatography in the coronal and oblique–coronal planes before and after fentanyl injection (every 2 up to 9 min). The images were analyzed qualitatively and quantitatively. Diameter and signal intensity were measured at the widest point and distal to the common bile duct and main pancreatic duct.

Results

The mean common bile duct diameters at the widest and distal points and mean pancreatic duct diameter were measured 7.53, 4.72, and 2.14 and 8.33, 5.35, and 2.57 before and after fentanyl injection, respectively. Mean signal intensity at the widest and distal point of the common bile duct and mean pancreatic duct signal intensity measured 278, 199, and 113 and 296, 218, and 121 before and after fentanyl injection, respectively. Minor improvements in image quality were detected qualitatively.

Conclusion

Fentanyl injection improves images qualitatively and quantitatively. In agreement with previous studies, our results confirm the beneficial effects of fentanyl as a simple adjunct to traditional magnetic resonance cholangiopancreatography.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Cohen SA, Siegel JH, Kasmin FE (1996) Complications of diagnostic and therapeutic ERCP. Abdom Imaging 21:385–394

    Article  PubMed  CAS  Google Scholar 

  2. Duncan HD, Hodgkinson L, Deakin M, et al. (1997) The safety of diagnostic and therapeutic ERCP as a daycare procedure with a selective admission policy. Eur J Gastroentrol Hepatol 9:905–908

    Article  CAS  Google Scholar 

  3. Edelman R, Hesselink J, Zlatkin M, et al. (2006) Clinical magnetic resonance imaging; third edition. Philadelphia: Saunders Elsevier, pp 2483–2540

    Google Scholar 

  4. Kaltenthaler EC, Walters SJ, Chilcott J, et al. (2006) MRCP compared to diagnostic ERCP for diagnosis when biliary obstruction is suspected: a systematic review. BMC Imaging 14:6–9

    Google Scholar 

  5. Shanmugam V, Beattie GC, Yule SR, et al. (2005) Is magnetic resonance cholangiopancreatography the new gold standard in biliary imaging? Br J Radiol 78:888–893

    Article  PubMed  CAS  Google Scholar 

  6. Silva AC, Friese JL, Hara AK, et al. (2004) MR cholangiopancreatography: improved ductal distention with intravenous morphine administration. Radiographics 24:677–687

    Article  PubMed  Google Scholar 

  7. Lee NJ, Kim KW, Kim TK, et al. (2006) Secretin-stimulated MRCP. Abdom Imaging 31:575–581

    Article  PubMed  CAS  Google Scholar 

  8. Agrawal S, Nag P, Sikora S, et al. (2006) Fentanyl-augmented MRCP. Abdom Imaging 31:582–587

    Article  Google Scholar 

  9. Chu ZQ, Ji Q, Zhang Jl (2010) Orally administered lemon/orange juice improved MRCP imaging of pancreatic ducts. Abdom Imaging 35:367–371

    Article  PubMed  Google Scholar 

  10. Fentanyl citrate dosage form: injection. http://drugs.com/pro/fentanyl-citrate.html

  11. Fig LM, Wahl RL, Stewart RE, et al. (1990) Morphine-augmented hepatobiliary scintigraphy in the severely ill: caution is in order. Radiology 175(2):467–473

    PubMed  CAS  Google Scholar 

  12. Matos C, Metens T, Devière J, et al. (1997) Pancreatic duct: morphologic and functional evaluation with dynamic MR pancreatography after secretin stimulation. Radiology 203:435–441

    PubMed  CAS  Google Scholar 

  13. Manfredi R, Costamagna G, Brizi MG, et al. (2000) Sever chronic pancreatitis versus suspected pancreatic disease: dynamic MR cholangiopancreatography after secretin stimulation. Radiology 214:849–855

    PubMed  CAS  Google Scholar 

  14. Hellund JC, Skattum J, Buanes T, et al. (2007) Secretin-stimulated magnetic resonance cholangiopancreatography of patients with unclear disease in the pancreaticoboliary tract. Acta Radiol 48:135–141

    Article  PubMed  CAS  Google Scholar 

  15. Czako L, Takacs T, Morvay Z, et al. (2004) Diagnostic value of secretin-enhanced magnetic resonance cholangiopancreatography (S-MRCP) after unsuccessful endoscopic retrograde cholangiopancreatography (ERCP). Orv Hetil 145:529–534

    PubMed  Google Scholar 

  16. Mc Cammon RL, Stoelting RK, Madura JA (1984) Effects of butorphanol, nalbuphine and fentanyl on intrabiliary tract dynamics. Anesth Analg 63:139–142

    CAS  Google Scholar 

Download references

Acknowledgments

This project was supported by a Grant from the Mazandaran University of Medical Sciences, Sari, Iran.

Conflict of interest

None of the authors has a conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Roohollah Abdi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Abdi, R., Fallah-Arzpeima, S. Pancreaticobiliary disorders: comparison between magnetic resonance cholangiopancreatography images before and after fentanyl injection. Abdom Imaging 38, 537–542 (2013). https://doi.org/10.1007/s00261-012-9937-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00261-012-9937-8

Keywords

Navigation