Abstract
Background
Emergent MRI is now a viable alternative to CT for evaluating appendicitis while avoiding the detrimental effects of ionizing radiation. However, primary employment of MRI in the setting of clinically suspected pediatric appendicitis has remained significantly underutilized.
Objective
To describe our institution’s development and the results of a fully implemented clinical program using MRI as the primary imaging evaluation for children with suspected appendicitis.
Materials and methods
A four-sequence MRI protocol consisting of coronal and axial single-shot turbo spin-echo (SS-TSE) T2, coronal spectral adiabatic inversion recovery (SPAIR), and axial SS-TSE T2 with fat saturation was performed on 208 children, ages 3 to 17 years, with clinically suspected appendicitis. No intravenous or oral contrast material was administered. No sedation was administered. Data collection includes two separate areas: time parameter analysis and MRI diagnostic results.
Results
Diagnostic accuracy of MRI for pediatric appendicitis indicated a sensitivity of 97.6% (CI: 87.1–99.9%), specificity 97.0% (CI: 93.2–99.0%), positive predictive value 88.9% (CI: 76.0–96.3%), and negative predictive value 99.4% (CI: 96.6–99.9%). Time parameter analysis indicated clinical feasibility, with time requested to first sequence obtained mean of 78.7 +/− 52.5 min, median 65 min; first-to-last sequence time stamp mean 14.2 +/− 8.8 min, median 12 min; last sequence to report mean 57.4 +/− 35.2 min, median 46 min. Mean age was 11.2 +/− 3.6 years old. Girls represented 57% of patients.
Conclusion
MRI is an effective and efficient method of imaging children with clinically suspected appendicitis. Using an expedited four-sequence protocol, sensitivity and specificity are comparable to CT while avoiding the detrimental effects of ionizing radiation.
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References
Hernanz-Schulman M (2010) CT and US in the diagnosis of appendicitis: an argument for CT. Radiology 255:3–7
Callahan M, Rodriguez D, Taylor G (2002) CT of appendicitis in children. Radiology 224:325–332
Brenner D, Hall E (2007) Computed tomography–an increasing source of radiation exposure. N Engl J Med 357:2277–2284
Strouse P (2010) Pediatric appendicitis: an argument for US. Radiology 255:8–13
Tkacz J, Anderson S, Soto J (2009) MR imaging in gastrointestinal emergencies. Radiographics 29:1767–1780
Hormann M, Paya K, Eibenberger K et al (1998) MR imaging in children with nonperforated acute appendicitis: value of unenhanced MR imaging in sonographically selected cases. AJR 171:467–470
Cobben L, Groot I, Kingma L et al (2009) A simple MRI protocol in patients with clinically suspected appendicitis: results in 138 patients and effect on outcome of appendectomy. Eur Radiol 19:1175–1183
Krishnamoorthi R, Ramarajan N, Wang N et al (2011) Effectiveness of a staged US and CT protocol for the diagnosis of pediatric appendicitis: reducing radiation exposure in the age of ALARA. Radiology 259:231–239
Edelstein W, Mahesh M, Carrino J (2010) MRI: time is dose–and money and versatility. JACR 7:650–652
Barger R, Nandalur K (2010) Diagnostic performance of magnetic resonance imaging in the detection of appendicitis in adults: a meta-analysis. Acad Radiol 17:1211–1216
Doria A, Moineddin R, Kellenberger C et al (2006) US or CT for diagnosis of appendicitis in children and adults? a meta-analysis. Radiology 241:83–94
Kaiser S, Frenckner B, Jorulf H (2002) Suspected appendicitis in children: US and CT—a prospective randomized study. Radiology 223:633–638
Baldisserotto M, Valduga S, da Cunha CF (2008) MR imaging evaluation of the normal appendix in children and adolescents. Radiology 249:278–284
Ganguli S, Raptopoulos V, Komlos F et al (2006) Right lower quadrant pain: value of the nonvisualized appendix in patients at multidetector CT. Radiology 241:175–180
Acknowledgments
We thank our pediatric surgical colleagues (Drs. Robert Cilley, Brett Engbrecht, Mary Santos, Dorothy Rocourt, Kerry Fagelman and Peter Dillon) for their support. We also thank Tim Elliot (Radiology Information Systems) for assistance with time parameter analysis and Allen Kunselman (Biostatistical Consulting Service) for statistical analysis. We are also grateful to all our MR technologists (including team leaders Jason Hatter, Joan Hartman and Dana Fortney).
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Moore, M.M., Gustas, C.N., Choudhary, A.K. et al. MRI for clinically suspected pediatric appendicitis: an implemented program. Pediatr Radiol 42, 1056–1063 (2012). https://doi.org/10.1007/s00247-012-2412-4
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DOI: https://doi.org/10.1007/s00247-012-2412-4