Skip to main content
Log in

A simple MRI protocol in patients with clinically suspected appendicitis: results in 138 patients and effect on outcome of appendectomy

  • Gastrointestinal
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

To establish the value of breathhold magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis. Over a 14-month period, 138 patients clinically suspected of having appendicitis were evaluated prospectively with MRI and comprised the study group. Fast turbo spin-echo breathhold T1, T2 and T2 fat suppression sequences were used in coronal and axial planes. The imaging results were recorded separately and subsequently correlated with clinical, radiological and histopathological follow-up. The effect of imaging strategies in patients suspected of appendicitis on hospital resources was calculated. Sixty-two of the 138 patients had a histopathologically proven appendicitis. MRI determined appendicitis in 63 patients, with one examination being false positive. The resulting sensitivity and specificity were 100% and 99%, respectively. MRI showed an alternative diagnosis in 41 of the 75 remaining patients. In 22 of the remaining 34 patients, a normal appendix was depicted with MRI. In two patients, where MRI showed no appendicitis, an alternative diagnosis or normal appendix, an unnecessary appendectomy was performed. The overall effect of using MRI in patients suspected of appendicitis on the use of hospital resources could have been a net saving between € 55,746 and € 72,534. MRI has a high accuracy in detecting and excluding appendicitis, an alternative diagnosis or showing the normal appendix, and can be a valuable and cost-effective tool in the workup of patients clinically suspected of having appendicitis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Ferrier PK (1972) Acute appendicitis in university students: a 20 year study of 1,028 cases. J Am Coll Health Assoc 20:287–290

    PubMed  CAS  Google Scholar 

  2. Jess P, Bjerregaard B, Brynitz S et al (1981) Acute appendicitis. Prospective trial concerning diagnostic accuracy and complications. Am J Surg 141:232–234

    Article  PubMed  CAS  Google Scholar 

  3. Lewis FR, Holcroft JW, Boey J et al (1975) Appendicitis; a critical review of diagnosis and treatment. Arch Surg 110:677–684

    PubMed  CAS  Google Scholar 

  4. Pieper R, Kager L, Nasman P (1982) Acute appendicitis: a clinical study of 1,018 cases of emergency appendectomy. Acta Chir Scand 148:51–62

    PubMed  CAS  Google Scholar 

  5. Silberman VA (1981) Appendectomy in a large metropolitan hospital. Retrospective analysis of 1,013 cases. Am J Surg 142:615–618

    Article  PubMed  CAS  Google Scholar 

  6. Doria AS, Moineddin R, Kellenberger CJ et al (2006) US or CT for diagnosis of appendicitis in children and adults? A meta-analysis. Radiology 241:83–94

    Article  PubMed  Google Scholar 

  7. Lee JH, Jeong YK, Park KB et al (2005) Operator-dependent techniques for graded compression sonography to detect the appendix and diagnose acute appendicitis. AJR Am J Roentgenol 184:91–97

    PubMed  Google Scholar 

  8. Pohl D, Golub R, Schwartz GE et al (1998) Appendiceal ultrasonography performed by nonradiologists: does it help in the diagnostic process? J Ultrasound Med 17:217–221

    PubMed  CAS  Google Scholar 

  9. McCollough CH, Schueler BA, Atwell TD et al (2007) Radiation exposure and pregnancy: when should we be concerned? Radiographics 27:909–917 discussion 917–8

    Article  PubMed  Google Scholar 

  10. Dixon AK, Dendy P (1998) Spiral CT: how much does radiation dose matter? Lancet 352:1082–1083

    Article  PubMed  CAS  Google Scholar 

  11. Zoetelief J, Geleijns J (1998) Patient doses in spiral CT. Br J Radiol 71:584–586

    PubMed  CAS  Google Scholar 

  12. Brenner DJ, Hall EJ (2007) Computed tomography—an increasing source of radiation exposure. N Engl J Med 357:2277–2284

    Article  PubMed  CAS  Google Scholar 

  13. Cobben LP, Groot I, Haans L et al (2004) MRI for clinically suspected appendicitis during pregnancy. AJR Am J Roentgenol 183:671–675

    PubMed  Google Scholar 

  14. Hormann M, Paya K, Eibenberger K et al (1998) MR imaging in children with nonperforated acute appendicitis: value of unenhanced MR imaging in sonographically selected cases. AJR 171:467–470

    PubMed  CAS  Google Scholar 

  15. Hormann M, Puig S, Prokesch SR et al (2002) MR imaging of the normal appendix in children. Eur Radiol 12:2313–2316

    PubMed  CAS  Google Scholar 

  16. Incesu L, Coskun A, Selcuk MB et al (1997) Acute appendicitis: MR imaging and sonographic correlation. AJR 168:669–674

    PubMed  CAS  Google Scholar 

  17. Nitta N, Takahashi M, Furukawa A et al (2005) MR imaging of the normal appendix and acute appendicitis. J Magn Reson Imaging 21:156–165

    Article  PubMed  Google Scholar 

  18. Oto A, Ernst RD, Shah R et al (2005) Right-lower-quadrant pain and suspected appendicitis in pregnant women: evaluation with MR imaging—initial experience. Radiology 234:445–451

    Article  PubMed  Google Scholar 

  19. Pedrosa I, Levine D, Eyvazzadeh AD et al (2006) MR imaging evaluation of acute appendicitis in pregnancy. Radiology 238:891–899

    Article  PubMed  Google Scholar 

  20. Moteki T, Horikoshi H (2007) New CT criterion for acute appendicitis: maximum depth of intraluminal appendiceal fluid. AJR Am J Roentgenol 188:1313–1319

    Article  PubMed  Google Scholar 

  21. Rosai J (1996) Chapter 11: Appendix. In: Ackerman"s Surgical Pathology, 8. Mosby, St Louis, pp 711–716

    Google Scholar 

  22. Gaitini D, Beck-Razi N, Mor-Yosef D et al (2008) Diagnosing acute appendicitis in adults: Accuracy of color Doppler sonography and MDCT compared with surgery and clinical follow-up. Am J Roentgenol 190:1300–1306

    Article  Google Scholar 

  23. van Breda Vriesman AC, Kole BJ, Puylaert JB (2003) Effect of ultrasonography and optional computed tomography on the outcome of appendectomy. Eur Radiol 13:2278–2282

    Article  PubMed  Google Scholar 

  24. Birnbaum BA, Wilson SR (2000) Appendicitis at the millennium. Radiology 215:337–348

    PubMed  CAS  Google Scholar 

  25. Jones PF (2001) Suspected acute appendicitis: trends in management over 30 years. Br J Surg 88:1570–1577

    Article  PubMed  CAS  Google Scholar 

  26. Colson M, Skinner KA, Dunnington G (1997) High negative appendectomy rates are no longer acceptable. Am J Surg 174:723–726 discussion 726–727

    Article  PubMed  CAS  Google Scholar 

  27. Temple CL, Huchcroft SA, Temple WJ (1995) The natural history of appendicitis in adults. A prospective study. Ann Surg 221:278–281

    Article  PubMed  CAS  Google Scholar 

  28. Keyzer C, Zalcman M, De Maertelaer V et al (2005) Comparison of US and unenhanced multi-detector row CT in patients suspected of having acute appendicitis. Radiology 236:527–534

    Article  PubMed  Google Scholar 

  29. Nikolaidis P, Hammond N, Marko J et al (2006) Incidence of visualization of the normal appendix on different MRI sequences. Emerg Radiol 12:223–226

    Article  PubMed  Google Scholar 

  30. Eldar S, Nash E, Sabo E et al (1997) Delay of surgery in acute appendicitis. Am J Surg 173:194–198

    Article  PubMed  CAS  Google Scholar 

  31. Rao PM, Rhea JT, Novelline RA et al (1998) Effect of computed tomography of the appendix on treatment of patients and use of hospital resources. N Engl J Med 338:141–146

    Article  PubMed  CAS  Google Scholar 

  32. Axelrod DA, Sonnad SS, Hirschl RB (2000) An economic evaluation of sonographic examination of children with suspected appendicitis. J Pediatr Surg 35:1236–1241

    Article  PubMed  CAS  Google Scholar 

  33. Bijnen CL, Van Den Broek WT, Bijnen AB et al (2003) Implications of removing a normal appendix. Dig Surg 20:215–221

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lodewijk Cobben.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cobben, L., Groot, I., Kingma, L. et al. A simple MRI protocol in patients with clinically suspected appendicitis: results in 138 patients and effect on outcome of appendectomy. Eur Radiol 19, 1175–1183 (2009). https://doi.org/10.1007/s00330-008-1270-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00330-008-1270-9

Keywords

Navigation