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Cow colostrum and early milk enriched with eicosapentaenoic and docosahexaenoic fatty acid

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Abstract

The objective of the study was to explore whether it is possible to alter cow colostrum and early milk fatty acid composition with a low level of fat supplement, high in docosahexaenoic (DHA) and eicosapentaenoic (EPA) fatty acid. Diets included a control diet and a diet supplemented with DHA- and EPA-enriched fat supplement. Addition of fat supplement significantly decreased saturated fatty acids, C14:0 and C16:0 and increased the values of monounsaturated fatty acids, polyunsaturated fatty acids (PUFA), n3 fatty acids, EPA, DHA, C18:1n9cis and C18:1n11trans. The percentage of short-chain fatty acids significantly increased with the progress of lactation, while the percentage of PUFA, n3 and n6 significantly decreased. These results showed that fat supplement, high in DHA and EPA, modified the fatty acid profile of colostrum and milk fat and increased the proportion of beneficial fatty acids for human health.

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References

  1. Segall JJ (1977) Is milk a coronary health hazard? Br J Prev Soc Med 31:81–85

    CAS  Google Scholar 

  2. Keys A, Anderson JT, Grande F (1965) Serum cholesterol response to changes in the diet. IV Particular saturated fatty acids in the diet. Metabolism 14:776–787

    Article  CAS  Google Scholar 

  3. Hegsted DM, McGandy RB, Myers SM, Stare FJ (1965) Quantitative effects of dietary fat on serum cholesterol in man. Am J Clin Nutr 17:237–242

    Google Scholar 

  4. Noakes M, Nestel PJ, Clifton PM (1996) Modifying the fatty acid profile of dairy products through feedlot technology lowers plasma cholesterol of humans consuming the products. Am J Clin Nutr 63:42–46

    CAS  Google Scholar 

  5. Sir-Tarino PW, Sun Q, Hu FB, Kraus RM (2010) Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am J Clin Nutr 91:535–546

    Article  Google Scholar 

  6. Horrocks LA, Yeo YK (1999) Health benefits of docosahexaenoic acid (DHA). Pharmacol Res 40:211–225

    Article  CAS  Google Scholar 

  7. Ip C, Singh M, Thompson HJ, Scimeca JA (1994) Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of mammary gland in the rat. Cancer Res 54:1212–1215

    CAS  Google Scholar 

  8. Rodríguez-Alcalá LM, Fontecha J, De la Hoz L, Nunes da Silva VS, Carvalho JE, Bertoldo Pacheco MT (2013) CLA-enriched milk powder reverses hypercholesterolemic risk factors in hamsters original research article. Food Res Int 51:244–249

    Article  Google Scholar 

  9. Whigham LD, Watras AC, Schoeller DA (2007) Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans. Am J Clin Nutr 85:1203–1211

    CAS  Google Scholar 

  10. Playford RJ, Floyd DN, Macdonald CE, Calnan DP, Adenekan RO, Johnson W, Goodlad RA, Marchbank T (1999) Bovine colostrum is a health food supplement which prevents NSAID-induced gut damage. Gut 44:653–658

    Article  CAS  Google Scholar 

  11. Marchbank T, Davison G, Oakes JR, Ghatei MA, Patterson M, Moyer MP, Playford RJ (2011) The nutriceutical bovine colostrum truncates the increase in gut permeability caused by heavy exercise in athletes. Am J Physiol Gastrointest Liver Physiol 300:G477–G484

    Article  CAS  Google Scholar 

  12. Hofman Z, Smeets R, Verlaan G, Lugt RV, Verstappen PA (2002) The effect of bovine colostrum supplementation on exercise performance in elite field hockey players. Int J Sport Nutr Exerc Metab 12:461–469

    Google Scholar 

  13. Ferlay A, Doreau M, Martin C, Chilliard Y (2013) Effects of incremental amounts of extruded linseed on the milk fatty acid composition of dairy cows receiving hay or corn silage. J Dairy Sci 96:6577–6595

    Article  CAS  Google Scholar 

  14. Puppel K, Nałęcz-Tarwacka T, Kuczyńska B, Gołębiewski M, Grodzki H (2012) Influence of combined supplementation of cows’ diet with linseed and fish oil on the thrombogenic and atherogenic indicators of milk fat. Animal Sci Pap Rep 30:317–328

    CAS  Google Scholar 

  15. Vahmani P, Fredeen AH, Glover KE (2013) Effect of supplementation with fish oil or microalgae on fatty acid composition of milk from cows managed in confinement or pasture systems. J Dairy Sci 96:6660–6670

    Article  CAS  Google Scholar 

  16. Donovan DC, Schingoethe DJ, Baer RJ, Ryali J, Hippen AR, Franklin ST (2000) Influence of dietary fish oil on conjugated linoleic acid and other fatty acids in milk fat from lactating dairy cows. J Dairy Sci 83:2620–2628

    Article  CAS  Google Scholar 

  17. AbuGhazaleh AA, Potu RB, Ibrahim S (2009) The effect of substituting fish oil in dairy cow diets with docosahexaenoic acid micro algae on milk composition and fatty acids profile. J Dairy Sci 92:6156–6159

    Article  CAS  Google Scholar 

  18. Glover KE, Budge S, Rose M, Rupasinghe HPV, MacLaren L, Green-Johnson J, Fredeen AH (2012) Effect of feeding fresh forage and marine algae on the fatty acid composition and oxidation of milk and butter. J Dairy Sci 95:2797–2809

    Article  CAS  Google Scholar 

  19. Hara A, Radin NS (1978) Lipid extraction of tissues with a low-toxicity solvent. Anal Biochem 90:420–426

    Article  CAS  Google Scholar 

  20. Rule DC (1997) Direct transesterification of total fatty acids of adipose tissue, and of freeze-dried muscle and liver with boron-trifluoride in methanol. Meat Sci 46:23–32

    Article  CAS  Google Scholar 

  21. Fletouris DJ, Botsoglou NA, Psomas IE, Mantis AI (1998) Rapid determination of cholesterol in milk and milk products by direct saponification and capillary gas chromatography. J Dairy Sci 81:2833–2840

    Article  CAS  Google Scholar 

  22. Ulbright TLV, Southgate DAT (1991) Coronary heart disease: seven dietary factors. Lancet 338:985–992

    Article  Google Scholar 

  23. Baer RJ, Ryali J, Schingoethe DJ, Kasperson KM, Donovan DC, Hippen AR, Franklin ST (2001) Composition and properties of milk and butter from cows fed fish oil. J Dairy Sci 84:345–353

    Article  CAS  Google Scholar 

  24. Franklin ST, Martin KR, Baer RJ, Schingoethe DJ, Hippen AR (1999) Dietary marine algae (Schizochytrium sp.) increase concentrations of conjugated linoleic, docosahexaenoic and transvaccenic acids in milk of dairy cows. J Nutr 129:2048–2054

    CAS  Google Scholar 

  25. Marounek M, Pavlata L, Mišurova L, Volek Z, Dvořak R (2012) Changes in the composition of goat colostrum and milk fatty acids during the first month of lactation. Czech J Anim Sci 57:28–33

    CAS  Google Scholar 

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Acknowledgments

This work was supported by a grant of the Ministry of Science, Education and Sports of the Republic of Croatia, in the projects “Mineral metabolism of domestic animals in high production and stress” No. 053-1080229-2104 and “The influence of nutraceuticals on the health and performance of food animals” No. 053-0532265-2244.

Conflict of interest

None.

Compliance with Ethics Requirements

All procedures with animals were approved by the Ethics Committee of the Faculty of Veterinary Medicine and the Ministry of Agriculture, Forestry and Water Management of Republic of Croatia (Class UP/I 322-01/07-01/108, No 525-6-07-2).

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Authors and Affiliations

  1. Department of Animal Nutrition and Dietetics, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10000, Zagreb, Croatia

    Tomislav Mašek & Diana Brozić

  2. Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10000, Zagreb, Croatia

    Luka Krstulović & Miroslav Bajić

  3. Department of Crop, Forage and Grassland Production, Faculty of Agriculture, Centre of Grassland Production, University of Zagreb, Svetošimunska cesta 25, 10000, Zagreb, Croatia

    Marina Vranić

  4. Department of Animal Husbandry, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10000, Zagreb, Croatia

    Maja Maurić & Kristina Starčević

Authors
  1. Tomislav Mašek
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  2. Luka Krstulović
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  3. Diana Brozić
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  4. Marina Vranić
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  5. Maja Maurić
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  6. Miroslav Bajić
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  7. Kristina Starčević
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Corresponding author

Correspondence to Kristina Starčević.

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Mašek, T., Krstulović, L., Brozić, D. et al. Cow colostrum and early milk enriched with eicosapentaenoic and docosahexaenoic fatty acid. Eur Food Res Technol 238, 635–640 (2014). https://doi.org/10.1007/s00217-013-2144-1

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  • DOI: https://doi.org/10.1007/s00217-013-2144-1

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