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Vitrifikation vs. „slow freezing“

Was bringt die besseren Ergebnisse?

Vitrification vs. slow freezing

What yields better results?

  • Leitthema
  • Published:
Der Gynäkologe Aims and scope

Zusammenfassung

Für die Kryokonservierung von humanen Oozyten, Blastozysten sowie Embryonen werden hauptsächlich 2 Methoden angewandt: das langsame Einfrieren oder „slow freezing“ sowie das ultrarapide Einfrieren, auch „Vitrifikation“ genannt. Über die letzten Jahrzehnte hinweg hat die Vitrifikation das „slow freezing“ aus den meisten In-vitro-Fertilisations(IVF)-Zentren weltweit verdrängt. Eine Ursache für diese Entwicklung ist die Überlebensrate der Oozyten, Blastozysten und Embryonen nach dem Auftauen, die mit nahezu 100 % bei Weitem die Rate übersteigt, die nach dem „slow freezing“ erreicht wird (~40–60 %). Im vorliegenden Artikel werden beide Methoden beschrieben und hinsichtlich der Methodik sowie der Resultate verglichen.

Abstract

For cryopreservation of human oocytes, blastocysts, and embryos, two methods are mainly employed: slow freezing and ultra-rapid freezing, also known as vitrification. Over the past decades, the vitrification procedure has replaced slow-freezing in most in vitro fertilization (IVF) centers worldwide. One reason for this development is the survival rate after thawing the oocytes, blastocysts, and embryos, which at nearly 100%, far exceeds the survival rate achieved after slow freezing (~40–60%). In this article, both procedures will be described and compared with regard to methodology and outcome.

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Author information

Authors and Affiliations

  1. IVF-Consulting, Vorwiesenweg 7, 23560, Lübeck, Deutschland

    S. Al-Hasani

  2. Dritte Universitätsfrauenklinik, Thessaloniki, Griechenland

    V. Palapelas

  3. Emeritierter Direktor der Frauenklinik Lübeck, Lübeck, Deutschland

    K. Diedrich

Authors
  1. S. Al-Hasani
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  2. V. Palapelas
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  3. K. Diedrich
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Corresponding author

Correspondence to S. Al-Hasani.

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Interessenkonflikt

S. Al-Hasani, V. Palapelas und K. Diedrich geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Redaktion

K. Diedrich, Hamburg

R. Felberbaum, Kempten

W. Küpker, Bühl

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Al-Hasani, S., Palapelas, V. & Diedrich, K. Vitrifikation vs. „slow freezing“. Gynäkologe 50, 433–440 (2017). https://doi.org/10.1007/s00129-017-4073-8

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  • DOI: https://doi.org/10.1007/s00129-017-4073-8

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