Summary
The membranes of both mouse and cod islets contain a protein phosphokinase enzyme. 3′,5′-cyclic AMP, ouabain, phosphoenolpyruvate and glucose-6-phosphate enhance protein phosphokinase activity. Protein kinase which is membrane bound is unable to use exogenous protein (histone) as a substrate and phosphorylates specific proteins in the membranes. These proteins have been partially characterized.
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Davis, B., Lazarus, N.R. Regulation of 3′,5′-cyclic AMP-dependent protein kinase in the plasma membrane of cod (Gadus callarius) and mouse islets. J. Membrain Biol. 20, 301–318 (1975). https://doi.org/10.1007/BF01870640
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DOI: https://doi.org/10.1007/BF01870640