Summary
Phospholipase A serum activity was prospectively studied in 39 patients with multiple trauma. There was no correlation of phospholipase A activity with type or severity of injury. With increasing phospholipase A levels, a rise in mortality was found. A prediction of fatal outcome on an individual basis was not possible. The sensitivity for complications was 90%, whereas the predictive value of the positive test (64%) and specificity (47%) were low. When the behavior of phospholipase A and elastase release were compared, no correlation between these two parameters could be detected. Therefore, PMN leukocytes do not seem to be a major source of phospholipase A in serum.
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Waydhas, C., Nast-Kolb, D., Duswald, K.H. et al. Prognostic value of serum phospholipase a in the multitraumatized patient. Klin Wochenschr 67, 203–206 (1989). https://doi.org/10.1007/BF01711354
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DOI: https://doi.org/10.1007/BF01711354