Abstract
Phosphoglucomutase (PGM) of red cells was examined in 15 inbred strains of mice, using two different starch gel electrophoretic buffer systems. Two new alleles, Pgm-1 c and Pgm-1 d, were discovered at the Pgm-1 locus. Pgm-1 c was first identified in strain C3H/HeNWe and Pgm-1 d in 129/ReWl. No variation was observed at the Pgm-2 locus.
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Brewer, G. J., Bowbeer, D. R., and Tashian, R. E. (1967). The electrophoretic phenotypes of red cell phosphoglucomutase, adenylate kinase, and acid phosphatase in the American Negro. Acta Genet. (Basel) 1797.
Chapman, V. M., Ruddle, F. H., and Roderick, T. H. (1971). Linkage of isozyme loci in the mouse: Phosphoglucomutase-2 (Pgm-2), mitochondrial NADP malate dehydrogenase (Mod-2), and dipeptidase-1 (Dip-1). Biochem. Genet. 5101.
Hutton, J. J., and Roderick, T. H. (1970). Linkage analyses using biochemical variants in mice. III. Linkage relationships of eleven biochemical markers. Biochem. Genet. 4339.
Miner, G. D. (1969). Mouse News Letter, No. 40, p. 32.
Parrington, J. M., Cruickshank, G., Hopkinson, D. A., Robson, E. B., and Harris, H. (1968). Linkage relationships between the three phosphoglucomutase loci PGM1, PGM2, and PGM3. Ann. Hum. Genet. (Lond.) 3227.
Shows, T. B., Tashian, R. E., Brewer, G. J., and Dern, R. J. (1964). Erythrocyte glucose-6-phosphate dehydrogenase in Caucasians: New inherited variant. Science 1451056.
Shows, T. B., Ruddle, F. H., and Roderick, T. H. (1969). Phosphoglucomutase electrophoretic variants in the mouse. Biochem. Genet. 325.
Spencer, N., Hopkinson, D. A., and Harris, H. (1964). Phosphoglucomutase polymorphism in man. Nature 204742.
Susor, W. A., Kochman, M., and Rutter, W. J. (1969). Heterogeneity of presumably homogeneous protein preparations. Science 1651260.
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Supported in part by USPHS Pre-doctoral Fellowship No. 5 F1 GM-32,680, USPHS Research Resources Grant No. 5-PO6 RR 00343-05, USPHS (National Cancer Institute) Chemotherapy Contract 71-2010, and Biomedical Sciences Support Grant FR 07037 to the University of Kansas.
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Miner, G.D., Wolfe, H.G. Phosphoglucomutase isozymes of red cells in Mus musculus: Additional polymorphism at PGM-1 compared by two electrophoretic systems. Biochem Genet 7, 247–252 (1972). https://doi.org/10.1007/BF00484823
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DOI: https://doi.org/10.1007/BF00484823