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The nature of the genetic determinant for the SHV-1 β-lactamase

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Summary

In two unrelated plasmids of incompatibility groups FII and N the gene for the SHV-1 β-lactamase exists as part of a transposable element of molecular weight 9.5 megadaltons. This transposon has moved onto plasmids of at least three incompatibility groups; PI, Iα and J. This confirms the suggestion that the recent spread of the SHV-1 β-lactamase has been associated with the transposition of the genetic determinant of this enzyme between unrelated plasmids.

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Authors and Affiliations

  1. Department of Bacteriology, Royal Postgraduate Medical School, W 12, London, England

    M. E. Nugent & R. W. Hedges

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  1. M. E. Nugent
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  2. R. W. Hedges
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Communicated by J. Schell

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Nugent, M.E., Hedges, R.W. The nature of the genetic determinant for the SHV-1 β-lactamase. Molec. gen. Genet. 175, 239–243 (1979). https://doi.org/10.1007/BF00397222

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  • DOI: https://doi.org/10.1007/BF00397222

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