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Variation in tritiated thymidine uptake during DNA synthesis in the adrenal cortex

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Summary

The interphase grain counts of adrenocortical cells labelled with tritiated thymidine (3H) Tdr,do not conform to a Poisson distribution, and therefore are not the result of a random disintegration process. The rate of (3H) Tdr incorporation during interphase DNA synthesis (the S phase) was studied by metaphase grain count analysis. Maximum rates of incorporation were found towards the middle of the S phase. The interphase grain count of adrenocortical cells is considered to be largely dependent on the position of the cell in the S phase.

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  1. Department of Pathology, University of Newcastle upon Tyne, UK

    N. A. Wright

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  1. N. A. Wright
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Wright, N.A. Variation in tritiated thymidine uptake during DNA synthesis in the adrenal cortex. Histochemie 28, 99–102 (1971). https://doi.org/10.1007/BF00279854

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  • DOI: https://doi.org/10.1007/BF00279854

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