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Mossy and climbing fibre activation in the cat cerebellum by stimulation of the labyrinth

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Summary

In decerebrate cats, caloric and galvanic stimulations of the labyrinth were able to modulate the activity of the Purkinje cells through both the afferents which terminate in the cerebellar cortex as mossy fibres and climbing fibres.

In response to these stimulations, several patterns of response were seen. For the galvanic stimulation a predominant pattern was described. In most cases the mossy fibre driven activity had an effect which was opposite to that of the climbing fibre one.

The climbing fibre driven activity could be modulated only in the low frequency range, but it can interfere remarkably with the mossy fibre one. The results described were obtained not only in the so-called vestibular area of the cerebellum, but also in other areas.

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Authors and Affiliations

  1. Istituto di Fisiologia Umana dell'Università di Pisa e Laboratorio di Neurofisiologia del C.N.R., Pisa, Italy

    M. Ferin, R. A. Grigorian & P. Strata

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  1. M. Ferin
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  2. R. A. Grigorian
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  3. P. Strata
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From the International Institute for the Study of Human Reproduction, College of Physicians and Surgeons, Columbia University, New York, N.Y. 10032 USA.

From the Sechenov Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences of USSR, Leningrad K-223, Thorez pr. 52, USSR.

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Ferin, M., Grigorian, R.A. & Strata, P. Mossy and climbing fibre activation in the cat cerebellum by stimulation of the labyrinth. Exp Brain Res 12, 1–17 (1971). https://doi.org/10.1007/BF00234413

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