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Future of Orthopaedic Sports Medicine and Soft Tissue Healing: The Important Role of Engineering

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Abstract

The practice of orthopaedic sports medicine, specifically the management of ligament and tendon injuries, will experience dramatic changes in the near future. Rapid technological advancements, especially in imaging, will greatly increase the speed and accuracy of diagnosing musculoskeletal injuries. On the contrary, effective treatment strategies will lag behind. This widening gap will offer huge opportunities for clinicians, basic scientists, and bioengineers to collaborate and work jointly on in depth basic science and bioengineering research. Together with appropriately designed clinical outcome studies, scientifically based treatment strategies can be designed in order to reduce the gap and to improve patient outcome. In this review, we will focus on the subject of orthopaedic biomechanics and its importance in the treatment of ligament and tendon injuries. We will detail the history of fundamental work done to characterize their biomechanical properties and highlight some recent advances using functional tissue engineering strategies, including the use of bioscaffolds, to improve the healing of medial collateral ligament, patellar tendon, and anterior cruciate ligament. To conclude, we will turn toward the future and highlight a few exciting areas of research as well as emphasize collaborative strategies to solve complex biological and biomechanical problems in ligaments and tendons.

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Acknowledgments

The authors acknowledge the financial support provided by the National Institute of Health (AR41820 and AR39683) and National Science Foundation (Engineering Research Center, #0812348). We also wish to acknowledge the research contributions of past and present members of the Musculoskeletal Research Center as well as our collaborators, Dr. Michael Torry and Dr. Richard Steadman, of the Steadman-Hawkins Research Foundation.

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  1. Musculoskeletal Research Center, Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, 405 Center for Bioengineering, 300 Technology Drive, Pittsburgh, PA, 15219, USA

    Savio L-Y. Woo, Rui Liang & Matthew B. Fisher

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Woo, S.LY., Liang, R. & Fisher, M.B. Future of Orthopaedic Sports Medicine and Soft Tissue Healing: The Important Role of Engineering. Cel. Mol. Bioeng. 2, 448–461 (2009). https://doi.org/10.1007/s12195-009-0065-7

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