Cellular and Molecular Life Sciences

, 66:3277

Polyunsaturated fatty acids and cardiovascular disease

  • Doriane Richard
  • Pedro Bausero
  • Charlotte Schneider
  • Francesco Visioli
Review

DOI: 10.1007/s00018-009-0085-4

Cite this article as:
Richard, D., Bausero, P., Schneider, C. et al. Cell. Mol. Life Sci. (2009) 66: 3277. doi:10.1007/s00018-009-0085-4

Abstract

Replacing saturated with polyunsaturated (PUFAs) rather than monounsaturated fatty acids or carbohydrates results in cardiovascular prevention over a wide range of intakes. The mechanisms by which PUFAs reduce cardiovascular risk are manifold, and the extent and precise nature of their activities is the subject of several investigations, spanning from in vitro mechanistic studies to human intervention trials. This article reviews the most up-to-date evidence of the association between PUFA consumption and reduced cardiovascular mortality.

Keywords

Fatty acidsCardiovascular diseaseOmega 3Omega 6CholesterolInflammation

Copyright information

© Birkhäuser Verlag, Basel/Switzerland 2009

Authors and Affiliations

  • Doriane Richard
    • 1
  • Pedro Bausero
    • 1
  • Charlotte Schneider
    • 1
  • Francesco Visioli
    • 1
  1. 1.Laboratory of Micronutrients and Cardiovascular DiseaseUniversité Pierre et Marie CurieParisFrance