Abstract
We have measured, by an intubation method, gastric evacuation and gastrointestinal absorption of alcohol ingested with a meal in seven healthy nonalcoholic subjects. A homogenized meal containing [14C]PEG and ethanol (1 g/kg body wt) was given intragastrically while saline containing [57CO]vitamin B12 was perfused into the duodenum. Of the ingested alcohol, 39.4±4.1% was absorbed through the stomach wall during the first postprandial hour and 73.2±4.2% during the total postcibal period, whereas only 24±3% was absorbed during the same time in the duodenum. Thus alcohol ingested with a meal is mainly and rapidly absorbed in the stomach; the contribution of the small intestine below the angle of Treitz to alcohol absorption is negligible.
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Cortot, A., Jobin, G., Ducrot, F. et al. Gastric emptying and gastrointestinal absorption of alcohol ingested with a meal. Digest Dis Sci 31, 343–348 (1986). https://doi.org/10.1007/BF01311667
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DOI: https://doi.org/10.1007/BF01311667