Skip to main content

Advertisement

SpringerLink
Log in

Multiple myeloma presenting with pyomyositis caused by community-acquired methicillin-resistant Staphylococcus aureus: report of a case and literature review

  • Case Report
  • Published:
International Journal of Hematology Aims and scope Submit manuscript

Abstract

Pyomyositis is infrequently reported in patients with multiple myeloma. Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is emerging as an important cause of soft tissue infections, including pyomyositis. Here, we report on the first case of CA-MRSA pyomyositis in a patient with multiple myeloma and review the relevant literature.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Sirohi B, Powles R. Multiple myeloma. Lancet. 2004;363:875–87.

    Article  PubMed  Google Scholar 

  2. Paradisi F, Corh G, Cinelli R. Infections in multiple myeloma. Infect Dis Clin North Am. 2001;15:373–84.

    Article  CAS  PubMed  Google Scholar 

  3. Savage DG, Lindenbaum J, Garret TJ. Biphasic pattern of bacterial infection in multiple myeloma. Ann Intern Med. 1982;96:47–50.

    Article  CAS  PubMed  Google Scholar 

  4. Sarubbi FA, Gafford GD, Bishop DR. Gram-negative bacterial pyomyositis: unique case and review. Rev Infect Dis. 1989;11:789–92.

    Article  CAS  PubMed  Google Scholar 

  5. Prallet B, Cartry O, Tonolli I, et al. Bacterial pyomyositis in a patient with a multiple myeloma. Clin Rheumatol. 1992;11:424–6.

    Article  CAS  PubMed  Google Scholar 

  6. Korten V, Gurbuz O, Firatli T, Bayik M, Akoglou T. Subcutaneous nodules caused by Pseudomonas aeruginosa: healing without incision and drainage. J Chemother. 1992;4:225–7.

    Article  CAS  PubMed  Google Scholar 

  7. Hoyle C, Goldman M. Pyomyositis in a patient with myeloma responding to antibiotics alone. J Intern Med. 1993;233:419–21.

    Article  CAS  PubMed  Google Scholar 

  8. Katagiri K, Shibuya H, Takayasu S. Bacteroides fragilis pyomyositis in a patient with multiple myeloma. J Dermatol. 1996;23:129–32.

    Article  CAS  PubMed  Google Scholar 

  9. Cone LA, Lamb RB, Graff-Radford A, et al. Pyomyositis of the anterior tibial compartment. Clin Infect Dis. 1997;25:146–8.

    Article  CAS  PubMed  Google Scholar 

  10. Matsuno O, Matsumoto T, Miyazaki E, Nakagawa H, Kumamoto T, Tsuda T. Pyomyositis associated with Bacteroides fragilis in a patient with multiple myeloma. Am J Trop Med Hyg. 1998;59:42–4.

    Article  CAS  PubMed  Google Scholar 

  11. Moran JG, Krishnadasan A, Gorwitz JR, et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med. 2006;355:666–74.

    Article  CAS  PubMed  Google Scholar 

  12. Tristan F, Etienne J. Community acquired MRSA in Europe. BMJ. 2007;335:947–8.

    Article  Google Scholar 

  13. Fan HC, Lo WT, Chu ML, Wang CC. Clinical characteristics of Staphylococcal pyomyositis. J Microbiol Immunol Infect. 2002;35:121–4.

    PubMed  Google Scholar 

  14. Ruiz ME, Yohannes S, Wladyka CG. Pyomyositis caused by methicillin-resistant Staphylococcus aureus. N Engl J Med. 2005;352:1488–9.

    Article  CAS  PubMed  Google Scholar 

  15. Fowler A, Mackay A. Community-acquired methicillin-resistant Staphylococcus aureus pyomyositis in an intravenous drug user. J Med Microbiol. 2006;55:123–5.

    Article  CAS  PubMed  Google Scholar 

  16. Martin-Millan M, Garcia-Ibarbia C, Gutierrez-Cuadra M, et al. Pyomyositis: retrospective review in a third-level hospital in the north of Spain. Enferm Infecc Microbiol Clin. 2006;24:173–7.

    Article  PubMed  Google Scholar 

  17. Small LN, Ross JJ. Tropical and temperate pyomyositis. Infect Dis Clin North Am. 2005;19:981–9.

    Article  PubMed  Google Scholar 

  18. Tristan A, Bes M, Meugnier H, et al. Global distribution of Panton–Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus. Emerg Infect Dis. 2007;13:594–600.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Naimi TS, LeDell KH, Como-Sabetti K, et al. Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection. JAMA. 2003;290:2976–84.

    Article  CAS  PubMed  Google Scholar 

  20. Issartel B, Tristan A, Lechevallier S, et al. Frequent carriage of Panton–Valentine leukocidin genes by Staphylococcus aureus isolates from surgically drained abscesses. J Clin Microbiol. 2005;43:3203–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Lina G, Piemont Y, Godail-Gamot F, et al. Involvement of Panton–Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis. 1999;29:1128–32.

    Article  CAS  PubMed  Google Scholar 

  22. Davis SL, Perri B, Donabedian SM, et al. Epidemiology and outcomes of community-associated methicillin-resistant Staphylococcus aureus infection. J Clin Microbiol. 2007;45:1705–11.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Twomey JJ. Infections complicating multiple myeloma and chronic lymphocytic leukemia. Arch Intern Med. 1973;132:562–5.

    Article  CAS  PubMed  Google Scholar 

  24. Hargreaves RM, Lea JR, Griffiths H, et al. Immunological factors and risk of infection in plateau phase myeloma. J Clin Pathol. 1995;48:260–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Perri RT, Hebbel RP, Oken MM. Influence of treatment and response status on infection risk in multiple myeloma. J Am Med Assoc. 1981;71:935–40.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. First Division of Internal Medicine, Medical School of Ioannina, University Hospital, 45110, Ioannina, Greece

    Georgios Kalambokis, Areti Theodorou & Epameinondas V. Tsianos

  2. Department of Radiology, University Hospital, Ioannina, Greece

    Paraskevi Kosta

Authors
  1. Georgios Kalambokis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Areti Theodorou
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Paraskevi Kosta
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Epameinondas V. Tsianos
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Epameinondas V. Tsianos.

About this article

Cite this article

Kalambokis, G., Theodorou, A., Kosta, P. et al. Multiple myeloma presenting with pyomyositis caused by community-acquired methicillin-resistant Staphylococcus aureus: report of a case and literature review. Int J Hematol 87, 516–519 (2008). https://doi.org/10.1007/s12185-008-0100-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12185-008-0100-9

Keywords

Search

Navigation