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Evaluation of mass-like consolidation after stereotactic body radiation therapy for lung tumors

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Abstract

Background

The purpose of this study was to evaluate the characteristics of mass-like consolidation of the lung on computed tomography (CT) after stereotactic body radiation therapy (SBRT) retrospectively.

Methods

Forty lung tumors in 37 patients who underwent SBRT were evaluated. Mass-like consolidation was defined as a dense consolidation that newly appeared over or around the original tumor, which included radiation-induced lung injury (RILI) and local recurrence. Time of appearance, initial CT findings (ectatic bronchi and conformity to dose distribution) and serial changes in the size of the mass-like consolidation were evaluated.

Results

Mass-like consolidation appeared in 27 (68%) of 40 tumors at a median of 5 months after SBRT. Follow-up examination revealed that 24 (89%) of the 27 mass-like consolidations were RILI and 3 (11%) were local recurrence. There were no significant differences in the initial CT findings between RILI and local recurrence. The size of the mass-like consolidation varied in the 12 months after SBRT. After 12 months or more, however, the size did not increase in any of the RILI cases, but it did increase in all recurrence cases.

Conclusion

Mass-like consolidations were observed in 68% of cases at a median of 5 months after SBRT. Although most of the mass-like consolidations were RILI, local recurrence was observed in a few cases. Early detection of local recurrence after SBRT was difficult.

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Authors and Affiliations

  1. Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan

    Yukinori Matsuo, Yasushi Nagata, Takashi Mizowaki, Kenji Takayama, Takashi Sakamoto, Yoshiki Norihisa & Masahiro Hiraoka

  2. Department of Radiation Oncology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan

    Takashi Sakamoto

  3. Department of Radiology, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan

    Masato Sakamoto

Authors
  1. Yukinori Matsuo
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  2. Yasushi Nagata
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  3. Takashi Mizowaki
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  4. Kenji Takayama
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  5. Takashi Sakamoto
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  6. Masato Sakamoto
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  7. Yoshiki Norihisa
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  8. Masahiro Hiraoka
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Corresponding author

Correspondence to Yasushi Nagata.

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Cite this article

Matsuo, Y., Nagata, Y., Mizowaki, T. et al. Evaluation of mass-like consolidation after stereotactic body radiation therapy for lung tumors. Int J Clin Oncol 12, 356–362 (2007). https://doi.org/10.1007/s10147-007-0691-9

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  • DOI: https://doi.org/10.1007/s10147-007-0691-9

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