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Electron microscopic observation on osteocytes of chronically alcoholized rats

  • Clinical and Experimental Forum
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Summary

Adult female Wistar rats were alcoholized with 5% to 20% of ethyl alcohol from 2 months onwards for 1 year. The alcohol was added to the drinking water.

The animals were reared under conventional conditions. Their ossa femura were used for electron microscopical studies. Pathologic findings on osteocytes are described.

Zusammenfassung

Adulte weibliche Wistar-Ratten wurde mit 5 his 20% Äthanol im Alter von 2 Monaten ein Jahr lang alkoholisiert. Der Alkohol wurde dem Trinkwasser zugeftügt.

Die Haltung der Tiere erfolgte unter konventionellen Bedingungen. Die Ossa femura wurden elektronenmikroskopisch untersucht.

Pathologische Befunde der Osteocyten werden beschrieben.

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References

  • Dalen N, Feldreich A (1974) Osteopenia in alcoholism. Clin Orth Rel Res 99:201–202

    Article  Google Scholar 

  • Dalen N, Lamke C (1976) Bone mineral losses in alcoholics. Acta Orthop Scand 47:469–471

    Article  PubMed  CAS  Google Scholar 

  • Dudley H, Spiro D (1961) The fine structure of bone cells. J Biophys Biochem Cytol 11:627–649

    Article  PubMed  CAS  Google Scholar 

  • Jänicke-Lorenz J, Lorenz R, Bartsch H (1982) The rat as a model in alcohol research. Z Versuchstierk 24:42–43

    Google Scholar 

  • Jande S, Belanger L (1973) The life cycle of the osteocyte. Clin Orthop 94:281–305

    PubMed  Google Scholar 

  • Knese K-H (1979) Handbuch der mikroskopischen Anatomie des Menschen. Stützgewebe und Skelettsystem. Springer, Berlin Heidelberg NewYork, S 599

    Google Scholar 

  • Lorenz R, Jänicke-Lorenz J, Bartsch H (1982) Zur vergleichenden Morphologie des chronischen Alkoholismus bei Ratte und Mensch. Zentralbl Vet Med (C) 11:375

    Google Scholar 

  • Lorenz R, Jänicke-Lorenz J (1983) Die Knochenbruchheilung bei der alkoholisierten Laboratoriumsratte (in press)

  • Mezey E, Potter J, Merchant C (1979) Effect of ethanol feeding on bone composition in the rat. Am J Clin Nutr 32:25–29

    PubMed  CAS  Google Scholar 

  • Saville P, Lieber C (1965) Effect of alcohol on growth, bone density, and muscle magnesium in the rat. J Nutr 87:477–484

    PubMed  CAS  Google Scholar 

  • Scherft J (1972) The lamina limitans of the organic matrix of calcified cartilage and bone. J Ultrastruc Res 38:318–331

    Article  CAS  Google Scholar 

  • Venable J, Goggeshall R (1965) A simplified lead citrate stain for use in electron microscopy. J Cell Biol 25:407

    Article  PubMed  CAS  Google Scholar 

  • Wassermann F, Yaeger J (1965) Fine structure of the osteocyte capsule and of the wall of lacunae and canaliculi in bone. Z Zellforsch 67:636–652

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Institut für Veterinär-Anatomie, -Histologie und -Embryologie der Freien Universität Berlin, Koserstraße 20, D-1000, Berlin 33

    Renate Lorenz

  2. Zentrale Tierlaboratorien der Freien Universität Berlin, Krahmerstraße 6, D-1000, Berlin 45

    J. Jänicke-Lorenz

Authors
  1. Renate Lorenz
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  2. J. Jänicke-Lorenz
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Lorenz, R., Jänicke-Lorenz, J. Electron microscopic observation on osteocytes of chronically alcoholized rats. Arch. Orth. Traum. Surg. 102, 118–122 (1983). https://doi.org/10.1007/BF02498728

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  • DOI: https://doi.org/10.1007/BF02498728

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