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Model of ontogenetic variability of the functional state of the organism in different regimes of motor activity

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Abstract

This paper analyzes the results of the study of the long-term effect of physical exercising and sports in the age range, including late periods of human ontogeny, from the standpoint of the oxidative stress theory. To study the features of the ontogenetic variability of the functional state of the organism, a comparative study of the indices of the functional state of the organism was carried out under different regimes of motor activity at different age stages of development: in sport veterans who continue active motor activity after the termination of a sports career, in former sportsmen leading a sedentary lifestyle, in individuals engaged in recreational forms of exercise, and in individuals who were never regularly engaged in physical education. The contingent of male subjects of different ages also included former athletes and coaches of national teams for cyclical and game sports that require a predominant endurance. As a result of the study, a model was developed that reflects the features and mechanisms of ontogenetic variability of the functional state of the organism under the influence of different regimes of motor activity.

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References

  1. Apanasenko, G.L. and Ivashchenko, L.Ya., Regulation of wellness training or what is wrong with Paffenberger?, in Mezhdunarodnaya konferentsiya “Chelovek v mire sporta: novye idei, tekhnologii, perspektivy,” Tezisy dokladov (Int. Conf. “Sports and a Man: New Concepts, Technologies, and Prospects,” Abstracts of Papers), Moscow, 1998, vol. 2, p. 539.

    Google Scholar 

  2. Babaev, M.A., Lysenko, A.V., and Petrova, O.A., Features of professional sports activities and the risk of accelerated aging, Usp. Gerontol., 2010, vol. 23, no. 4, pp. 652–657.

    CAS  Google Scholar 

  3. Belozerova, L.M., Metody opredeleniya biologicheksogo vozrasta po umstvennoi i fizicheskoi rabotosposobnosti (Determination of Biological Age by Mental and Physical Performance), Perm: Permsk. Gos. Med. Akad., 2000.

    Google Scholar 

  4. Bukov, A.T., Myakotnykh, V.V., Khodasevich, L.S., et al., Influence of various regimes of motor activity on the age dynamics of the basic functional systems of the organism, Vopr. Kurortol., Fizioter., Lecheb., Fiz. Kul’t., 2010, no. 4, pp. 12–18.

    Google Scholar 

  5. Golubeva, E.Yu. and Danilova, R.I., The role of physical activity in the prevention of functional limitations in old age, Klin. Gerontol., 2010, vol. 15, no. 11, pp. 46–52.

    Google Scholar 

  6. Graevskaya, N.D., Sports and health, Teor. Prakt. Fiz. Kul’t., 1996, no. 4, pp. 49–54.

    Google Scholar 

  7. Dudina, E.A., Aerobic capabilities and health status: clinico-morphofunctional parallels, Teor. Prakt. Fiz. Kul’t., 2006, no. 1, pp. 8–16.

    Google Scholar 

  8. Ignat’ev, A.V., Specific processes of free radical oxidation of blood in the process of human adaptation to various types of physical activity, Extended Abstract of Cand. Sci. (Med.) Dissertation, Moscow, 2002.

    Google Scholar 

  9. Manukhina, E.B., Lyamina, N.P., Dolotovskaya, P.V., et al., The role of nitric oxide and oxygen free radicals in the pathogenesis of hypertension, Kardiologiya, 2002, no. 11, pp. 73–84.

    Google Scholar 

  10. Myakotnykh, V.V., Dvigatel’naya aktivnost’ i vozrastnaya involyutsiya funktsional’nykh vozmozhnostei cheloveka (Motion Activity and Age Involution of Human Functional Abilities), Sochi: Sochinsk. Gos. Univ., 2013.

    Google Scholar 

  11. Myakotnykh, V.V., Khodasevich, L.S., and Mel’tser, V.L., The influence of motor activity on the age-related involution of human functional capabilities, Usp. Gerontol., 2012, vol. 25, no. 4, pp. 648–653.

    Google Scholar 

  12. Myakotnykh, V.V., Khodasevich, L.S., and Konovalova, M.P., The influence of physical activity on immunological resistance and the rate of the body aging, Vopr. Kurortol., Fizioter., Lecheb., Fiz. Kul’t., 2009, no. 2, pp. 49–52.

    Google Scholar 

  13. Myakotnykh, V.V. The contradictions in the modern concept of wellness training, Teor. Prakt. Fiz. Kul’t., 2011, no. 11, p. 23.

    Google Scholar 

  14. Novosel’tsev, V.N. and Mikhal’skii, A.I., Mathematical modeling and aging: research program, Usp. Gerontol., 2009, vol. 22, no. 1, pp. 117–128.

    Google Scholar 

  15. Polozov, A.A., Slagaemye maksimal’noi prodolzhitel’nosti zhizni: chto novogo? (The Terms of Maximum Life Expectancy: What’s New?), Moscow: Sovetskii Sport, 2011.

    Google Scholar 

  16. Topuzov, I.A., The role of oxidative processes in the formation of sports cellulite and microtraumatism in athletes, Teor. Prakt. Fiz. Kul’t., 2001, no. 6, pp. 18–20.

    Google Scholar 

  17. Fomin, N.A., Adaptatsiya: obshchebiologicheskie i psikhofiziologicheskie osnovy (General Biological and Psychophysiological Principles of Adaptation), Moscow: Teoriya Praktika Fiz. Kul’tury, 2003.

    Google Scholar 

  18. Abraham, P., Saumet, J.L., and Chevalier, J.M., External iliac artery endofibrosis in athletes, Sport Med., 1997, vol. 24, pp. 221–226.

    Article  CAS  Google Scholar 

  19. Bergholm, R., Makimattila, S., and Valkonen, M., Intense physical training decreases circulating antioxidants and endotheliumdependent vasodilation in vivo, Atherosclerosis, 1999, vol. 145, pp. 341–349.

    Article  CAS  PubMed  Google Scholar 

  20. Cardoso, A.M., Martins, C.C., and Silva Fiorin, F., Physical training prevents oxidative stress in L-NAMEinduced hypertension rats, Cell Biochem. Funct., 2013, vol. 31, no. 2, pp. 136–151.

    Article  CAS  PubMed  Google Scholar 

  21. Franzoni, F., Plantinga, Y., and Femia, F.R., Plasma antioxidant activity and cutaneous microvascular endothelial function in athletes and sedentary controls, Biomed. Pharmacother., 2004, vol. 58, no. 8, pp. 432–436.

    Article  CAS  PubMed  Google Scholar 

  22. Friedenreich, C.M., Woolcott, C.G., and McTiernan, A., Alberta physical activity and breast cancer prevention trial: sex hormone changes in a year-long exercise intervention among postmenopausal women, J. Clin. Oncol., 2010, vol. 28, no. 9, pp. 1458–1466.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Grander, D.N., Microvascularresponse to ischemia/ reperfusion in normotensive and hypertensive rats, Hypertens, 1999, vol. 34, pp. 212–216.

    Article  Google Scholar 

  24. Higashi, Y., Sasaki, S., and Kurisu, S., Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endothelium-derived nitric oxide, Circulation, 1999, vol. 100, pp. 1194–1202.

    Article  CAS  PubMed  Google Scholar 

  25. Hugo, V.C., Oxidative Stress, Muscle Damage and Inflammation in Kayakers and Canoeists: Effects of Acute and Chronic Exercise and Antioxidants Supplementation, Porto: Univ. of Oporto, 2008.

    Google Scholar 

  26. Koller, A. and Kaley, G., Shear stress dependent regulation of vascular resistance in health and disease: role of endothelium, Endothelium, 1996, vol. 4, pp. 247–272.

    Article  CAS  Google Scholar 

  27. Masoro, E.J., Metabolism, in Handbook of the Biology of Aging, Finch, C.E. and Shneider, E.L., Eds., 2nd ed., New York: van Nostrand, 1985, pp. 540–557.

    Google Scholar 

  28. Radovanovic, D., Braticl, M., Nurkic, M., et al., Oxidative stress biomarker response to concurrent strength and endurance training, Gen. Physiol. Biophys., 2009, vol. 28, pp. 205–211.

    PubMed  Google Scholar 

  29. Peternelj, T. and Coombes, J., Antioxidant supplementation during exercise training: beneficial or detrimental?, Sports Med., 2011, vol. 41, no. 12, pp. 1043–1069.

    Article  PubMed  Google Scholar 

  30. Rajagopalan, S., Kurz, S., and Munzel, T., Angiotensin 11-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone, J. Clin. Invest., 1996, vol. 97, pp. 1916–1923.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. Stankovic, M. and Radovanovic, D., Oxidative stress and physical activity, Sport Logia, 2012, vol. 8, no. 1, pp. 1–11.

    Google Scholar 

  32. Wilson, M. and Whyte, G., Is life-long exercise damaging to the heart?, Br. J. Sports Med., 2012, vol. 46, no. 9, pp. 623–624.

    Article  PubMed  Google Scholar 

  33. Zembron-Lacny, A., Ostapiuk, J., Slowinska-Lisowska, M., Witkowski, K., and Szyszka, K., Pro-antioxidant ratio in healthy men exposed to muscle-damaging resistance exercise, J. Physiol. Biochem., 2008, vol. 64, no. 1, pp. 27–35.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Sochi State University, Sochi, 354000, Russia

    V. V. Myakotnyh & L. S. Khodasevich

  2. Research Center of Balneology and Rehabilitation, North Caucasian Federal Scientific Clinical Center, Federal Medical Biological Agency, Sochi, 354000, Russia

    L. S. Khodasevich

Authors
  1. V. V. Myakotnyh
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  2. L. S. Khodasevich
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Correspondence to V. V. Myakotnyh.

Additional information

Original Russian Text © V.V. Myakotnyh, L.S. Khodasevich, 2017, published in Uspekhi Gerontologii, 2017, Vol. 30, No. 2, pp. 200–207.

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Myakotnyh, V.V., Khodasevich, L.S. Model of ontogenetic variability of the functional state of the organism in different regimes of motor activity. Adv Gerontol 7, 201–207 (2017). https://doi.org/10.1134/S2079057017030110

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