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Effect of delta-sleep-inducing peptide on the functional activity of certain organs and tissues of rats in the physiological aging of an organism

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Abstract

This paper shows that the exogenous delta-sleep-inducing peptide (DSIP) injected subcutaneously into rats at an age of 2–24 months of postnatal development in a dose of 100 mg/kg of animal body weight in courses for five consecutive days each month has a hepatoprotective effect. DSIP does not affect the functional activity of the pancreas and is not involved in the regulation of calcium homeostasis in the physiological aging of an organism.

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Authors and Affiliations

  1. Southern Federal University, ul. Bol’shaya Sadovaya 105/42, Rostov-on-Don, 344006, Russia

    T. I. Bondarenko & E. A. Mayboroda

  2. Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117871, Russia

    I. I. Mikhaleva & I. A. Prudchenko

Authors
  1. T. I. Bondarenko
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  2. E. A. Mayboroda
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  3. I. I. Mikhaleva
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  4. I. A. Prudchenko
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Correspondence to T. I. Bondarenko.

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Original Russian Text © T.I. Bondarenko, E.A. Mayboroda, I.I. Mikhaleva, I.A. Prudchenko, 2012, published in Uspekhi Gerontologii, 2012, Vol. 25, No. 1, pp. 132–138.

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Bondarenko, T.I., Mayboroda, E.A., Mikhaleva, I.I. et al. Effect of delta-sleep-inducing peptide on the functional activity of certain organs and tissues of rats in the physiological aging of an organism. Adv Gerontol 3, 142–147 (2013). https://doi.org/10.1134/S2079057013020033

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  • DOI: https://doi.org/10.1134/S2079057013020033

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