Subcutaneous injections of exogenous delta sleep-inducing peptide in a dose of 100 μg/kg (monthly, 5-day courses) to rats of various age groups (2-24 months) were followed by an increase in the expression of genes for SOD 1 (Sod1) and glutathione peroxidase 1 (Gpx1) in the brain and nucleated blood cells. The expression of these genes was shown to decrease during physiological aging of the body.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 157, No. 5, pp. 634-637, May, 2014
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Kutilin, D.S., Bondarenko, T.I., Kornienko, I.V. et al. Effect of Delta Sleep-Inducing Peptide on the Expression of Antioxidant Enzyme Genes in the Brain and Blood of Rats during Physiological Aging. Bull Exp Biol Med 157, 616–619 (2014). https://doi.org/10.1007/s10517-014-2628-4
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DOI: https://doi.org/10.1007/s10517-014-2628-4