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Update on the Intraoperative OCT: Where Do We Stand?

  • Retina (J Fortun, Section Editor)
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Abstract

Purpose of Review

The purpose of this study is to summarize recent updates and discuss emerging technologies related to intraoperative optical coherence tomography (OCT) for posterior segment surgery.

Recent Findings

The development of microscope-integrated OCT technology has expanded the potential applications for intraoperative OCT in the operating room. Research has continued to support the potential impact of intraoperative OCT on surgical decision-making and the overall perceived value by surgeons for utilizing intraoperative OCT during vitreoretinal surgery. In addition, recent research in intraoperative OCT has expanded to emerging surgical procedures such as image-guided Argus II retinal prosthesis implant, subretinal gene/cell delivery, and transretinal retinochoroidal biopsy. Technology advancements, including software technologies, prototype non-metallic OCT compatible surgical instruments, and real-time 3-D OCT (4-D OCT) device using swept source technology have been developed. The recent emergence of digital surgery provides an additional opportunity for image-guided surgery utilizing real-time intraoperative OCT overlays onto 3-D digital visualization system for a comprehensive digital surgical theater.

Summary

Image-guided surgery with intraoperative OCT continues to evolve and expand as the technology becomes more refined and more widely available. Continued research is needed to further validate the role for image-guided surgery in enhancing surgical outcomes.

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Authors and Affiliations

  1. Ophthalmic Imaging Center, Cleveland Clinic, Cole Eye Institute, 9500 Euclid Ave, Cleveland, OH, 44195, USA

    Atsuro Uchida, Sunil K. Srivastava & Justis P. Ehlers

  2. Cleveland Clinic, Cole Eye Institute, 9500 Euclid Ave/i32, Cleveland, OH, 44195, USA

    Atsuro Uchida, Sunil K. Srivastava & Justis P. Ehlers

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  1. Atsuro Uchida
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Correspondence to Justis P. Ehlers.

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Conflict of Interest

Justis Ehlers reports grants from NIH; the Ohio Department of Development TECH-13-059 (JPE, SKS); Research to Prevent Blindness (Cole Eye Institutional Grant), an unrestricted travel grant from Alcon Novartis Hida Memorial Award 2015, funded by Alcon Japan Ltd. (AU); grants from Aerpio; personal fees from Leica, Zeiss, Santen, and Roche; and grants and personal fees from Genentech, Regeneron, Thrombogenics. In addition, Dr. Ehlers has a patent Volumetric segmentation of pathology issued, and a patent Microscope mount for OCT pending.

Sunil Srivastava reports grants from the Ohio Dept Development TECH-13-059; Research to Prevent Blindness (Cole Eye Institutional Grant); personal fees from Santen, Bausch and Lomb, and Allergan; grants and personal fees from Alcon, Zeiss; and grants from Gilead, outside the submitted work. In addition, Dr. Srivastava has a patent Volumetric segmentation of pathology issued, and a patent Microscope mount for OCT licensed to Leica.

Atsuro Uchida reports an unrestricted travel grant from the Alcon Novartis Hida Memorial Award 2015 funded by the Alcon Japan Ltd., outside the submitted work.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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Uchida, A., Srivastava, S.K. & Ehlers, J.P. Update on the Intraoperative OCT: Where Do We Stand?. Curr Ophthalmol Rep 6, 24–35 (2018). https://doi.org/10.1007/s40135-018-0160-9

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  • DOI: https://doi.org/10.1007/s40135-018-0160-9

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