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Pediatric Corneal Transplantation—Where Are We Heading?

  • Corneal Transplantation (P Hamrah, Section Editor)
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Abstract

Purpose of Review

Pediatric corneal transplantation is technically challenging. Recently, developments in adult corneal transplantations have been implemented in children. This article provides a historical perspective and reviews the latest developments in the field and, in doing so, aims to provide recommendations on the best practice for pediatric keratoplasties.

Recent Findings

Outcomes of conventional penetrating keratoplasties in children have improved due to technological advances in pre-operative assessments, evolution of intraoperative techniques, careful post-operative follow-up, and prompt complication management. Newer types of corneal transplantation, such as deep anterior lamellar keratoplasty and endothelial keratoplasties, have also been successfully adopted in children. Recent scientific breakthroughs in biosynthetic material and corneal cellular regeneration hold great promise in our treatment of pediatric corneal diseases in the future.

Summary

With careful case selection and standardized perioperative preparations, outcomes of pediatric keratoplasties can be optimized. Adaptation of newer surgical techniques and emerging research developments could revolutionize pediatric keratoplasty in the future.

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Authors and Affiliations

  1. Department of Ophthalmology and Visual Sciences, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada

    Simon S. M. Fung, Asim Ali & Kamiar Mireskandari

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  1. Simon S. M. Fung
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  2. Asim Ali
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  3. Kamiar Mireskandari
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Correspondence to Kamiar Mireskandari.

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Asim Ali reports grants from Physicians Services Incorporated, outside the submitted work. Kamiar Mireskandari reports other from Abvie, outside the submitted work. Simon Fung declares no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the topical collection on Corneal Transplantation

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Fung, S.S.M., Ali, A. & Mireskandari, K. Pediatric Corneal Transplantation—Where Are We Heading?. Curr Ophthalmol Rep 5, 23–37 (2017). https://doi.org/10.1007/s40135-017-0126-3

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