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Post COVID-19 vaccination medium vessel vasculitis: a systematic review of case reports

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Abstract

Purpose

Vaccinations are essential in minimizing the effects of global health crises including COVID-19 pandemic. This study investigates the potential association between COVID-19 vaccination and the occurrence of medium vessel vasculitis.

Methods

Several databases were utilized to conduct a comprehensive literature review. The studies were carefully evaluated to ensure their quality and eliminate any potential bias.

Results

After reviewing 935 search results and removing duplicates, we selected 10 case reports. We discovered that medium vessel vasculitis may occur after COVID-19 vaccination, typically appearing around 16.2 days after vaccination. The patients in the study had a median age of 43.5 years and were predominantly males (80%). Additionally, half of the cases were reported after the second dose of vaccination.

Conclusions

Vaccination-associated vasculitis is a rare yet possible complication of COVID-19 vaccination and lacks a clear treatment protocol.

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Data availability

Data supporting the findings of this study are available within the article as supplementary materials.

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Authors and Affiliations

  1. Department of Neurosurgery, Trivandrum Medical College, Thiruvananthapuram, India

    Vivek Sanker

  2. Department of Public Health, Adelphi University, Garden City, NY, USA

    Maneeth Mylavarapu

  3. Virgen Milagrosa University Foundation College of Medicine, San Carlos City, Philippines

    Prakash Gupta

  4. University of Texas, MD Anderson Cancer Center, Houston, TX, USA

    Naureen Syed

  5. Department of Internal Medicine, Pandit Deendayal Upadhyay Medical College, Churu, Rajasthan, India

    Maitri Shah

  6. MS4, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    Venkata Vamshi Krishna Dondapati

Authors
  1. Vivek Sanker
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  2. Maneeth Mylavarapu
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  3. Prakash Gupta
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  4. Naureen Syed
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  5. Maitri Shah
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  6. Venkata Vamshi Krishna Dondapati
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Contributions

Vivek Sanker: study concept, study design, data collection, data analysis, data interpretation, writing the paper. Maneeth Mylavarapu: study concept, data collection, data analysis, writing the paper. Prakash Gupta: study concept, data collection, data analysis, writing the paper. Naureen Syed: study concept, data analysis, writing the paper. Maitri Shah: study concept, data collection, data analysis, writing. Vamshi Krishna: study concept, data analysis, data interpretation, writing.

Corresponding author

Correspondence to Maneeth Mylavarapu.

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The authors have no conflict of interests to declare.

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Supplementary file1 (PDF 554 KB)

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Sanker, V., Mylavarapu, M., Gupta, P. et al. Post COVID-19 vaccination medium vessel vasculitis: a systematic review of case reports. Infection (2024). https://doi.org/10.1007/s15010-024-02217-w

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  • DOI: https://doi.org/10.1007/s15010-024-02217-w

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