References
Armulik A, Genove G, Betsholtz C. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Developmental cell. 2011;21(2):193–215. https://doi.org/10.1016/j.devcel.2011.07.001.
Cooke VG, LeBleu VS, Keskin D, Khan Z, O’Connell JT, Teng Y, et al. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012;21(1):66–81. https://doi.org/10.1016/j.ccr.2011.11.024.
Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N, et al. Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 2006;124(1):161–73. https://doi.org/10.1016/j.cell.2005.10.034.
Gerl K, Miquerol L, Todorov VT, Hugo CP, Adams RH, Kurtz A, et al. Inducible glomerular erythropoietin production in the adult kidney. Kidney Int. 2015;88(6):1345–55. https://doi.org/10.1038/ki.2015.274.
Nisancioglu MH, Mahoney WM Jr, Kimmel DD, Schwartz SM, Betsholtz C, Genove G. Generation and characterization of rgs5 mutant mice. Mol Cell Biol. 2008;28(7):2324–31. https://doi.org/10.1128/MCB.01252-07.
Zhu X, Bergles DE, Nishiyama A. NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development. 2008;135(1):145–57. https://doi.org/10.1242/dev.004895.
LeBleu VS, Taduri G, O’Connell J, Teng Y, Cooke VG, Woda C, et al. Origin and function of myofibroblasts in kidney fibrosis. Nat Med. 2013;19(8):1047–53. https://doi.org/10.1038/nm.3218.
Huang W, Zhao N, Bai X, Karram K, Trotter J, Goebbels S, et al. Novel NG2-CreERT2 knock-in mice demonstrate heterogeneous differentiation potential of NG2 glia during development. Glia. 2014;62(6):896–913. https://doi.org/10.1002/glia.22648.
Nikolakopoulou AM, Montagne A, Kisler K, Dai Z, Wang Y, Huuskonen MT, et al. Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss. Nat Neurosci. 2019;22(7):1089–98. https://doi.org/10.1038/s41593-019-0434-z.
Guo X, Ge T, Xia S, Wu H, Colt M, Xie X, et al. Atp13a5 marker reveals pericytes of the central nervous system in mice. Available at SSRN: https://ssrn.com/abstract=3881359 or https://doi.org/10.2139/ssrn.3881359.
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This work was partially supported by the National Institutes of Health (NIH) Grants: R01HL146574, RF1AG065345, R21AG064422, and R21AG073862.
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Yao, Y. Challenges in Pericyte Research: Pericyte-Specific and Subtype-Specific Markers. Transl. Stroke Res. 13, 863–865 (2022). https://doi.org/10.1007/s12975-022-01018-3
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DOI: https://doi.org/10.1007/s12975-022-01018-3