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Collaboration of Cerebello-Rubral and Cerebello-Striatal Loops in a Motor Preparation Task

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Abstract

In this study, we used fMRI to identify brain regions associated with concentration (sustained attention) during a motor preparation task. In comparison with a non-concentration task, increased activities were observed (P < 0.05, FWE-corrected P values) in cerebellar lobules VI and VII, motor cortex, pre-supplementary motor area (pre-SMA), thalamus, red nucleus (RN), and caudate nucleus (CN). Moreover, analysis of effective connectivity inter-areal (psychophysiological interactions) showed that during preparation, concentration-related brain activity increase was dependent on Cerebello-thalamo-pre-SMA-RN and Pre-SMA-CN-thalamo-M1 loops. We postulate that, while pre-SMA common to both loops is specifically involved in the movement preparation and readiness for voluntary movement through the striatum, the cerebellar lobule VI in conjunction with RN, likely through a cerebellar-rubro-olivary-cerebellar loop, might be implicated in concentration-related optimization of upcoming motor performances.

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Authors and Affiliations

  1. Centre de Recherches sur le Sport et le Mouvement, (CeRSM - EA 2931), UFR STAPS, UPL, Université Paris Nanterre, 200 avenue de la république, 92000, Nanterre, France

    Chama Belkhiria, Eya Mssedi, Tarak Driss & Giovanni de Marco

  2. Service de Neuro-Imagerie, Hôpital des Quinze-Vingts, UPMC Paris 6, 28, rue de Charenton, 75012, Paris, France

    Christophe Habas

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  1. Chama Belkhiria
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Correspondence to Chama Belkhiria.

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Belkhiria, C., Mssedi, E., Habas, C. et al. Collaboration of Cerebello-Rubral and Cerebello-Striatal Loops in a Motor Preparation Task. Cerebellum 18, 203–211 (2019). https://doi.org/10.1007/s12311-018-0980-z

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