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Spindle Cell Lipoma Arising from the Supraglottis: A Case Report and Review of the Literature

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Abstract

Lipomas are common benign mesenchymal neoplasms. Although 13% of lipomas are found in the head and neck, only 0.6% have been reported in the larynx. Of all lipomas, the spindle cell variant is the least common. In the present study, we report a case of supraglottic spindle cell lipoma and review the literature of laryngeal spindle cell lipoma. A 35-year-old male presented with dysphagia and dyspnea and was found to have bilateral supraglottic lesions causing airway obstruction. The masses were resected endoscopically. Final pathology demonstrated mature adipocytes and spindle cells, with immunohistochemical patterns supportive of spindle cell lipoma. Spindle cell lipomas have rarely been reported in the upper airway. To our knowledge, this is the youngest patient reported to date. These lipomas are uncommon benign neoplasms and should be distinguished from aggressive mesenchymal neoplasms such as liposarcoma variants to guide appropriate conservative but curative therapy.

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Authors and Affiliations

  1. Department of Head and Neck Surgery, University of California Los Angeles, Los Angeles, CA, USA

    Shaghauyegh S. Azar, Floyd Buen & Elliot Abemayor

  2. Department of Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, CA, USA

    Jennifer J. Chia, Justin Caron, Sarah Dry & Sunita Bhuta

  3. Department of Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA

    Yue Ma

  4. David Geffen School of Medicine, University of California Los Angeles, 10833 Le Conte Ave., CHS 62-132, Los Angeles, CA, 90025, USA

    Shaghauyegh S. Azar

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  1. Shaghauyegh S. Azar
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  2. Floyd Buen
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  3. Jennifer J. Chia
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  4. Yue Ma
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  7. Sunita Bhuta
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  8. Elliot Abemayor
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Correspondence to Shaghauyegh S. Azar.

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This study was deemed exempt by the Institutional Review Board at the University of California, Los Angeles due to the de-identified nature of the report.

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Azar, S.S., Buen, F., Chia, J.J. et al. Spindle Cell Lipoma Arising from the Supraglottis: A Case Report and Review of the Literature. Head and Neck Pathol 15, 1299–1302 (2021). https://doi.org/10.1007/s12105-020-01259-4

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  • DOI: https://doi.org/10.1007/s12105-020-01259-4

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