Abstract
Objective
The aim of this study is to analyze the early outcomes of Total Arterial Revascularization using Robot Assisted Minimally Invasive Coronary Artery Bypass at our center between June 2019 and January 2023.
Methods
This is a retrospective analysis of 195 patients who underwent Total Arterial Coronary Revascularization through Robot Assisted Minimally Invasive Coronary Artery Bypass procedure (RA-CABG) during the period of June 2019 and January 2023 in a quaternary care center in India. Primary outcome variables were in-hospital and 30-day mortality. Secondary outcome variables included duration of surgery, length of intensive care unit (ICU) stay, in-hospital stay and perioperative morbidity. The entire patient population was divided into two groups for a subgroup analysis based on when the surgery was conducted i.e. the years since the robotic program was begun at our institution with 81 patients in group I (2019–2021), and 114 patients in group II (2022–2023).
Results
195 patients [88.7% male, mean age of 61.34 ± 9.58 years] underwent RA-CABG during the 5-year period (2019–2023) by a single experienced surgeon and his team. Conversion to larger thoracic incisions was required in 5 cases (2.59%). In-hospital and 30-day mortality was 1.02% each. The average length of ICU stay and hospital stay were 2.82 ± 1.17 days and 5.84 ± 1.71 days respectively. The duration of ICU stay correlated with the number of internal mammary artery grafts procured (p = 0.0022). Median duration of follow-up was 11 months. Overall mortality was 3.62% and cardiac related mortality was 2.07%, and 5 patients (2.59%) underwent percutaneous coronary intervention. Results of the sub-group analysis revealed a statistically significant difference between the groups in terms of number of internal mammary artery grafts procured (p = 0.010), need for transfusions (p = 0.00031), ICU stay (p = 0.0005) and in-hospital stay (p = 0.0006).
Conclusions
Total Arterial Coronary Revascularization through RA-CABG is a viable procedure in select patients. An experienced surgeon and team are required. Further studies in the form of randomized trials with long term follow-up are required to establish the overall utility, effectiveness and benefits to the patients.
Similar content being viewed by others
Data availability
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
References
Prabhakaran D, Jeemon P, Sharma M, Roth GA, Johnson C, Harikrishnan S, et al. The changing patterns of cardiovascular diseases and their risk factors in the states of India: the Global Burden of Disease Study 1990–2016. Lancet Glob Health [Internet]. 2018;6:e1339–51. Available from: https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(18)30407-8/fulltext. https://doi.org/10.1016/S2214-109X(18)30407-8. Accessed 14 Mar 2023.
Yusuf S, Hawken S, Ounpuu S. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet. 2004;13:15-6.3. https://doi.org/10.1016/S0140-6736(04)17018-9.
Bachar BJ, Manna B. Coronary Artery Bypass Graft [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2023 Mar 25]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK5078364. Accessed 14 Mar 2023.
Lawton JS, Tamis-Holland JE, Bangalore S, Bates ER, Beckie TM, Bischoff JM, et al. ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2021;2022:145. https://doi.org/10.1161/CIR.0000000000001039.
Otsuka F, Yahagi K, Sakakura K, Virmani R. Why is the mammary artery so special and what protects it from atherosclerosis? Ann Cardiothorac Surg [Internet]. 2013 ;2:519–26. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741888/. https://doi.org/10.3978/j.issn.2225-319X.2013.07.06. Accessed 14 Mar 2023.
Lee CW, Ahn JM, Cavalcante R, Sotomi Y, Onuma Y, Suwannasom P, et al. Coronary artery bypass surgery versus drug-eluting stent implantation for left main or multivessel coronary artery disease. JACC Cardiovasc Interv. 2016;9:2481–9. https://doi.org/10.1016/j.jcin.2016.10.008.
Chandrasekharan DP, Taggart DP. Informed consent for interventions in stable coronary artery disease: problems, etiologies, and solutions. Eur J Cardiothorac Surg. 2011;39:912–7. https://doi.org/10.1016/j.ejcts.2010.08.033.
Yanagawa F, Perez M, Bell T, Grim R, Martin J, Ahuja V. Critical outcomes in nonrobotic vs robotic-assisted cardiac surgery. JAMA Surg. 2015;150:771. https://doi.org/10.1001/jamasurg.2015.1098.
Pettinari M, Gianoli M, Palmen M, Cerny S, Onan B, Singh S, et al. Robotic coronary revascularization in Europe, state of art and future of EACTS-endorsed Robotic Cardiothoracic Surgery Taskforce. Interact Cardiovasc Thorac Surg. 2022;35. https://doi.org/10.1093/icvts/ivac108.
Calafiore AM, Giammarco GD, Teodori G, Bosco G, D’Annunzio E, Barsotti A, et al. Left anterior descending coronary artery grafting via left anterior small thoracotomy without cardiopulmonary bypass. Ann Thorac Surg. 1996;61:1658–63. Available from: https://pubmed.ncbi.nlm.nih.gov/8651765/. https://doi.org/10.1016/0003-4975(96)00187-7. Accessed 14 Mar 2023.
Subramanian VA. Less invasive arterial CABG on a beating heart. Ann Thorac Surg. 1997;63:S68-71. https://doi.org/10.1016/s0003-4975(97)00417-7.
Hemli JM, Patel NC. Robotic cardiac surgery. Surg Clin North Am. 2020;100:219-36. https://doi.org/10.1016/j.suc.2019.12.005.
Mohr FW, Falk V, Diegeler A, Autschback R. Computer-enhanced coronary artery bypass surgery. J Thorac Cardiovasc Surg. 1999;117:1212–4. https://doi.org/10.1016/s0022-5223(99)70261-8.
Loulmet D, Carpentier A, d’Attellis N, Berrebi A, Cardon C, Ponzio O, et al. Endoscopic coronary artery bypass grafting with the aid of robotic assisted instruments. J Thorac Cardiovasc Surg. 1999;118:4–10. https://doi.org/10.1016/S0022-5223(99)70133-9.
Guran E, Amabile A, Torregrossa G. Robotic coronary artery bypass grafting: history, current technique, and future perspectives [Internet]. www.intechopen.com. IntechOpen; 2021 [cited 2023 Mar 25]. Available from: https://www.intechopen.com/chapters/77907. Accessed 14 Mar 2023.
Meccariello G, Faedi F, AlGhamdi S, Montevecchi F, Firinu E, Zanotti C, et al. An experimental study about haptic feedback in robotic surgery: may visual feedback substitute tactile feedback? J Robot Surg. 2015;10:57–61. https://doi.org/10.1007/s11701-015-0541-0.
Serruys PW, Ong ATL, van Herwerden LA, Sousa JE, Jatene A, Bonnier JJRM, et al. Five-year outcomes after coronary stenting versus bypass surgery for the treatment of multivessel disease. J Am Coll Cardiol. 2005;46:575–81. https://doi.org/10.1016/j.jacc.2004.
Marin-Cuartas M, Sá MP, Torregrossa G, Davierwala PM. Minimally invasive coronary artery surgery: robotic and nonrobotic minimally invasive direct coronary artery bypass techniques. JTCVS Tech. 2021;10:170–7. https://doi.org/10.1016/j.xjtc.2021.10.008.
Gong W, Cai J, Wang Z, Chen A, Ye X, Li H, et al. Robot-assisted coronary artery bypass grafting improves short-term outcomes compared with minimally invasive direct coronary artery bypass grafting. J Thorac Dis. 2016;8:459–68. https://doi.org/10.21037/jtd.2016.02.67.
Gofus J, Cerny S, Shahin Y, Sorm Z, Vobornik M, Smolak P, et al. Robot-assisted vs. conventional MIDCAB: A propensity-matched analysis. Front Cardiovasc Med 2022;9:943076. Published 2022 Aug 30. https://doi.org/10.3389/fcvm.2022.943076.
Lin TH, Wang CW, Shen CH, Chang KH, Lai CH, Liu TJ, et al. Clinical outcomes of multivessel coronary artery disease patients revascularized by robot-assisted vs conventional standard coronary artery bypass graft surgeries in real-world practice. Medicine (Baltimore). 2021;100:e23830. https://doi.org/10.1097/MD.0000000000023830.
Piperata A, Busuttil O, Jansens JL, Modine T, Pernot M, Labrousse L. A single center initial experience with robotic-assisted minimally invasive coronary artery bypass surgery (RA-MIDCAB). J Pers Med. 2022;12:1895. Published 2022 Nov 12. https://doi.org/10.3390/jpm12111895.
Hammal F, Nagase F, Menon D, Ali I, Nagendran J, Stafinski T. Robot-assisted coronary artery bypass surgery: a systematic review and meta-analysis of comparative studies. Can J Surg. 2020;63:E491–508. https://doi.org/10.1503/cjs.013318.
Funding
None.
Author information
Authors and Affiliations
Contributions
Conceptualization, M.M.Y; methodology, M.M.Y, V.B.; validation, S.G. and D.K.; formal analysis, A.M.K.; data curation, M.M.Y, A.M.K; writing—original draft preparation, A.M.K.; writing—review and editing, A.M.K, V.B.; supervision, M.M.Y, S.G and D.K.; project administration, A.M.K. All authors have read and agreed to the published version of the manuscript.
Corresponding author
Ethics declarations
Institutional review board approval
The study was approved by the Institutional Review Board of Apollo Hospitals, Chennai (AMH-C-S-019/03-23).
Statement of human and animal rights
The study was conducted according to the guidelines of the Declaration of Helsinki.
Informed consent
Individual patient consent was waived as the study was a de-identified retrospective study.
Consent for publication
Not applicable.
Conflict of interest
The authors have no conflicts of interest to declare.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Yusuf, M.M., Bansal, V., Gunasekaran, S. et al. Total arterial revascularization using robot assisted minimally invasive coronary artery bypass: an Indian experience. Indian J Thorac Cardiovasc Surg 40, 42–49 (2024). https://doi.org/10.1007/s12055-023-01593-6
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12055-023-01593-6