Abstract
The application of natural and synthetic boron-containing compounds (BCC) in biomedical field is expanding. BCC have effects in the metabolism of living organisms. Some boron-enriched supplements are marketed as they exert effects in the bone and skeletal muscle; but also, BCC are being reported as acting on the enzymes and transporters of membrane suggesting they could modify the carbohydrate metabolism linked to some pathologies of high global burden, as an example is diabetes mellitus. Also, some recent findings are showing effects of BCC on lipid metabolism. In this review, information regarding the effects and interaction of these compounds was compiled, as well as the potential application for treating human metabolic disorders is suggested.
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The authors thank the scholarship for postgraduate students from Consejo Nacional de Ciencia y Tecnología and Instituto Politécnico Nacional.
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This study was supported by the Consejo Nacional de Ciencia y Tecnología and Secretaria de Investigación y Posgrado del Instituto Politécnico Nacional (M2143).
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M.A.S.U. and A.A.G. conceived the review. R.I.C.C. and F.C.R. collected and organized information. All authors wrote the drafts and main manuscript text. M.A.S.U. and A.A.G. prepared Figs. 1, 2, 3, 4, 5, 6, 7, and 8. All authors reviewed and edited the final manuscript.
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RI, CC., MF, CR., D, RV. et al. Boron-Containing Compounds for Prevention, Diagnosis, and Treatment of Human Metabolic Disorders. Biol Trace Elem Res 201, 2222–2239 (2023). https://doi.org/10.1007/s12011-022-03346-9
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DOI: https://doi.org/10.1007/s12011-022-03346-9