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The Alarming Rate of Malnutrition after Single Anastomosis Sleeve Ileal Bypass. A single Centre Experience

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Abstract

Background

Single anastomosis sleeve ileal (SASI) bypass is a modification of sleeve gastrectomy with transit bipartition (SG + TB). This study aims to assess the safety and efficacy of SASI as a primary metabolic and bariatric surgery (MBS).

Methods

This is a retrospective case series of 30 patients who underwent SASI bypass from January to December 2021. All patients completed at least 12 months of follow-up.

Results

Among the 30 patients, 93.3% were women, the mean age was 37.4 years, and the mean body mass index (BMI) was 45.6 kg/m2. The percentage of total body weight loss (TWL%) was 42.7%, the percent excess body weight loss (EWL%) was 92.7%, and the mean BMI at 12 months went from 45.6(35.2–58.4) to 25.8 kg/m2 (19.2–33.4). The obesity-associated complications remission rate was 87.5% for type 2 diabetes (T2D), 71.4% for hypertension (HTN) and 100% for obstructive sleep apnea (OSA). Thirteen patients (43.3%) had diarrhea, 7 (23.3%) had hypoalbuminemia, defined as serum albumin < 3 g/dl, and 6 (20%) underwent reversal of their index SASI. As for other nutritional issues, iron deficiency anemia was present in 21 patients (70%), while 19 patients (63.3%) had vitamin D, and 2(6.6%) had vitamin B12 deficiency.

Conclusion

Despite good short-term weight loss and improvement of obesity-associated complications, SASI is accompanied by high alarming malnutrition, even in short-term follow-up. Novel MBS should be judged for their long-term effects and compared to well-tested standard operations before they are used in routine clinical practice.

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Authors

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Correspondence to Ala Wafa.

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Conflict of interest

Ala Wafa and Ahmad Bashir have no conflict of interest.

Ricardo V Cohen Coordenador-Centro de Obesidade e Diabetes, Hospital.

Alemão Oswaldo Cruz, São Paulo. Director, The Center for Obesity and Diabetes, Oswaldo Cruz.

German Hospital, São Paulo, Brazil.

Ashraf Haddad is a consultant for Medtronic. RVC received research grants from Medtronic, Johnson&Johnson Medtech. Speaker for Medtronic, Johnson&Johnson Medtech and NovoNordisk. Scientific advisory board for Morphic Medical.

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Key Points

• SASI is a modification of SG + TB.

• Has good short-term weight loss, TWL% was 42.7%, and EWL% was 92.7%.

• Has good short-term improvement of obesity-associated complications.

• Is accompanied by high alarming malnutrition in short-term follow-up.

Supplementary Information

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Supplementary file1 (MP4 108262 KB)

Supplementary file2 (MP4 53695 KB)

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Wafa, A., Bashir, A., Cohen, R.V. et al. The Alarming Rate of Malnutrition after Single Anastomosis Sleeve Ileal Bypass. A single Centre Experience. OBES SURG 34, 1742–1747 (2024). https://doi.org/10.1007/s11695-024-07192-7

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