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Fast-Track Programs for Liver Surgery: A Meta-Analysis

  • Original Article
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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Background and Objectives

Plentiful publications have inspected the feasibility of fast-track surgery programs during hepatic surgery, but the potency of these studies has not been discussed profoundly so far. Our goal was to assess the effects of fast-track programs on surgical outcomes compared with traditional surgical plans for liver surgery.

Methods

The following databases were searched: PubMed, Cochrane library, Embase, Science Citation Index Expanded, etc. Studies meeting our inclusion criteria were included. All interrelated data and the methodological quality of included studies were extracted and assessed. We applied risk ratio and weighted mean difference as the estimated effect measures. Sensitivity analysis was performed to perceive the reliability of our findings.

Results

Altogether, 14 studies with 1400 patients were analyzed. Meta-analysis of randomized controlled trials demonstrated that implementation of fast-track surgery programs could observably decrease the total length of hospital stay, complication rate, postoperative first flatus time, and hospitalization expense, and did not compromise mortality and readmission rate. The above findings were also in line with the results of case-control studies.

Conclusions

Fast-track surgery programs are feasible and effective for liver surgery. Future studies should optimize fast-track surgery programs catering to liver surgery.

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Conflicts of interest

The authors declare that they have no conflict of interest.

Author contributions

Wu SJ and Cheng NS designed the study, Wu SJ and Cheng Y performed the literature research and collected the data; Wu SJ, Xiong XZ, Lu J and Lin YX assessed literature quality; Cheng NS, Wu SJ, Lu J, Lin YX and Zhou RX analyzed the data; Wu SJ wrote the paper.

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Authors and Affiliations

  1. Department of Bile Duct Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, Sichuan Province, China

    Si-Jia Wu, Xian-Ze Xiong, Jiong Lu, Yao Cheng, Yi-Xin Lin, Rong-Xing Zhou & Nan-Sheng Cheng

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  1. Si-Jia Wu
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  2. Xian-Ze Xiong
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Correspondence to Nan-Sheng Cheng.

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Wu, SJ., Xiong, XZ., Lu, J. et al. Fast-Track Programs for Liver Surgery: A Meta-Analysis. J Gastrointest Surg 19, 1640–1652 (2015). https://doi.org/10.1007/s11605-015-2879-z

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  • DOI: https://doi.org/10.1007/s11605-015-2879-z

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