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Comparison of a simple obstructive sleep apnea screening device with standard in-laboratory polysomnography

  • Sleep Breathing Physiology and Disorders • Original Article
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Abstract

Background

Obstructive sleep apnea (OSA) is a common underdiagnosed sleep disorder. Various strategies have been employed to easily screen for OSA. The ApneaStrip® (AS - S.L.P. Ltd, Tel Aviv, Israel) is an FDA approved OSA screening device applied to the upper lip at home. We evaluated the performance of this device against simultaneous in-laboratory polysomnography (PSG) in a group of well-characterized OSA patients.

Methods

Diagnostic PSG was performed in 56 patients (29 M, 37 F; age 48.9 ± 14.6 years; body mass index [BMI] 37.5 ± 9.0 kg/m2; apnea-hypopnea index—events/h—[AHI] 32.8 ± 22.9). The AS was applied and positioned to detect nasal and oral airflow. The AS gives a “positive” result for AHI ≥ 15. We examined the sensitivity and specificity of the AS against three thresholds derived from PSG: AHI ≥ 5, AHI ≥ 15 (company recommendation), and AHI ≥ 30.

Results

For PSG AHI ≥ 15, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the AS were 80, 54.5, 87.8, and 40 %, respectively. For PSG AHI ≥ 5, the values were 75.1, 66.7, 97.1, and 13.3 %, respectively. For PSG AHI ≥ 30, the values were 86.9, 36.2, 48.8, and 80 %, respectively. There were no significant modifying effects of age, BMI, gender, hypertension, diabetes, lung disease, and heart disease.

Conclusion

The AS has a high sensitivity for detection of OSA with AHI ≥ 15, but only modest specificity. The AS could be a useful component of an OSA screening program; however, negative results should be interpreted cautiously.

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Acknowledgments

We thank S.L.P Ltd for supplying the ApneaStrip devices. The study was performed at the University of Maryland, Baltimore.

Conflict of interest

The authors report no financial conflict of interest. All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

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Author notes

  1. Arkady Korotinsky

    Present address: Veterans Affairs Oxnard Clinic, Oxnard, CA, 93036, USA

Authors and Affiliations

  1. Sleep Disorders Center, Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, 100 N. Greene St 2nd Floor, Baltimore, MD, 21201, USA

    Samson Z. Assefa, Montserrat Diaz-Abad, Arkady Korotinsky & Steven M. Scharf

  2. Pharmaceutical Health Services Research Department, University of Maryland School of Pharmacy, Baltimore, MD, 21201, USA

    Sarah E. Tom

Authors
  1. Samson Z. Assefa
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  2. Montserrat Diaz-Abad
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  3. Arkady Korotinsky
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  4. Sarah E. Tom
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  5. Steven M. Scharf
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Corresponding author

Correspondence to Samson Z. Assefa.

Additional information

The abstract for this paper was presented at Sleep 2014 Meeting, Minneapolis, MN.

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Assefa, S.Z., Diaz-Abad, M., Korotinsky, A. et al. Comparison of a simple obstructive sleep apnea screening device with standard in-laboratory polysomnography. Sleep Breath 20, 537–541 (2016). https://doi.org/10.1007/s11325-015-1234-7

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  • DOI: https://doi.org/10.1007/s11325-015-1234-7

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