Abstract
Considering that current biotechnological advances have been contributing towards improving the well-being of humanity, endophytic fungi, such as Lasiodiplodia, are promising sources of new substances to be used in chemical, pharmaceutical and agrochemical processes. Bioactive secondary metabolites are examples of such substances, although it is widely known that Lasiodiplodia inflicts irreparable damage to several crops of major economic importance. They are often produced as a response against biotic and abiotic factors, thus revealing that they play different roles, such as in signaling and defense mechanisms. Therefore, this review presents a few subtle differences between pathogenicity and mutualistic endophyte-host interactions. Moreover, the main secondary metabolites produced by Lasiodiplodia endophytes have been described with respect to their relevant antimicrobial and cytotoxic activities.
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References
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Acknowledgements
This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001. Omar C. Gomez thanks the Program PEC-PG (Programa de Estudantes-Convênio de Pós-Graduação) provided by CAPES/CNPq—Brazil. Dajara M.B. Moreira is thankful for the scholarship granted by FAPEMIG.
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All the authors contributed to the Writing—Reviewing and Editing of the paper. JHHL had the idea for the article, OCG, DMBM, JHHL performed the literature search and data analysis and OCG and JHHL drafted and revised the work.
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Gómez, O.C., Moreira, D.M.B. & Luiz, J.H.H. Medicinal potentialities and pathogenic profile of Lasiodiplodia genus. World J Microbiol Biotechnol 37, 190 (2021). https://doi.org/10.1007/s11274-021-03137-9
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DOI: https://doi.org/10.1007/s11274-021-03137-9