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Microwave-assisted synthesis of 3-substituted-6-ferrocene methylene-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles

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Abstract

A series of triazolo-thiadiazole derivatives containing ferrocene were synthesized under microwave assistance. Compared with the phosphorus oxychloride method, the microwave method has the advantages of simple operation, short reaction time, fast reaction rate and high yield. The effects of different reaction conditions were explored, and under the optimized conditions, the products were obtained in good yields (up to 80%).

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Acknowledgements

We are grateful for the financial support from 973 preliminary Projects (2014CB260411) and the Key Laboratory project of Shaanxi Provincial Department of Education (13J017).

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Key Laboratory of Auxiliary Chemistry and Technology for Chemical Industry, Ministry of Education, Shaanxi University of Science and Technology, Xi’an, 710021, Shaanxi, China

    Yuting Liu, Hong Xin, Jingyi Yin & Dawei Yin

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  1. Yuting Liu
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  2. Hong Xin
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  3. Jingyi Yin
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  4. Dawei Yin
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Corresponding author

Correspondence to Hong Xin.

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Liu, Y., Xin, H., Yin, J. et al. Microwave-assisted synthesis of 3-substituted-6-ferrocene methylene-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles. Transit Met Chem 43, 381–385 (2018). https://doi.org/10.1007/s11243-018-0219-3

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  • DOI: https://doi.org/10.1007/s11243-018-0219-3

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