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Clinical efficacy of xenogeneic collagen matrix in augmenting keratinized mucosa round dental implants: a systematic review and meta-analysis

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Abstract

Objectives

This study aimed to evaluate the clinical effects of xenogeneic collagen matrix (XCM) in augmenting keratinized mucosa width (KMW) around dental implants.

Materials and methods

Articles that were published before or during April 2020 were electronically searched in four databases without any date or language restrictions and manually searched in regular journals and grey literature. The eligibility criteria comprised randomized controlled trials (RCTs) or prospective studies that analysed the clinical efficacy of XCM for augmenting KMW around dental implants. This systematic review (SR) was registered in PROSPERO under number CRD42018115399.

Results

Eleven studies published between 2009 and 2019 were included in this SR. There was no significant difference in KMW increase (p = 0.14), probing depth (PD) decrease (p = 0.17) or participants’ aesthetic satisfaction (PAS) (p = 0.32) when XCM was compared to connective tissue graft (CTG). However, the increase in gingival thickness (GT) was significantly higher (p = 0.001) with the use of CTG.

Conclusions

The use of XCM improved KMW and PD with rates comparable to those for CTG. XCM showed lower results for GT when compared to CTG. XCM presented similar results in terms of PAS when compared to CTG.

Clinical relevance

The presence of a KMW around dental implants is associated with better peri-implant tissue health.

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Authors and Affiliations

  1. Department of Periodontology, Dental Research Division, School of Dentistry, Veiga de Almeida University, Rua Ibituruna, 108, Maracanã, Rio de Janeiro, 20271-020, Brazil

    Vittorio Moraschini

  2. Department of Implantology, Brazilian Air Force, Odontoclínica de Aeronáutica Santos-Dumont, Praça Marechal âncora, 77, Centro, Rio de Janeiro, 20021-200, Brazil

    Heloisa Bailly Guimarães & Ingrid Chaves Cavalcante

  3. Department of Oral Surgery, School of Dentistry, Fluminense Federal University, Rua Mario dos Santos Braga, 30, Centro, Niterói, Rio de Janeiro, 24020-140, Brazil

    Monica Diuana Calasans-Maia

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  1. Vittorio Moraschini
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  2. Heloisa Bailly Guimarães
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  3. Ingrid Chaves Cavalcante
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  4. Monica Diuana Calasans-Maia
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Correspondence to Vittorio Moraschini.

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Moraschini, V., Guimarães, H.B., Cavalcante, I.C. et al. Clinical efficacy of xenogeneic collagen matrix in augmenting keratinized mucosa round dental implants: a systematic review and meta-analysis. Clin Oral Invest 24, 2163–2174 (2020). https://doi.org/10.1007/s00784-020-03321-5

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