Skip to main content

Advertisement

Log in

Ten years change in post-fracture care for hip fracture patients

  • Original Article
  • Published:
Journal of Bone and Mineral Metabolism Aims and scope Submit manuscript

Abstract

Introduction

This multicenter, retrospective study aimed to clarify the changes in postoperative care provided by orthopaedic surgeons after hip fractures and clarify the incidence of secondary fractures requiring surgery.

Materials and methods

Subjects were patients with hip fracture treated surgically in seven hospitals during the 10-year period from January 2008 to December 2017. Data on patient demographics, comorbidities, preoperative and postoperative osteoporosis treatments, and secondary fractures were collected from the medical records.

Results

In total, 4764 new hip fractures in 982 men and 3782 women (mean age: 81.3 ± 10.0 years) were identified. Approximately 10% of patients had a history of osteoporosis drug treatment and 35% of patients received postoperative drug treatment. The proportion of patients receiving postoperative drug therapy increased by approximately 10% between 2009 and 2010, 10% between 2010 and 2011, and 10% between 2011 and 2013. Although the rate of secondary fractures during the entire period and within 3 years decreased from 2011, the rate of secondary fracture within 1 year remained at around 2% every year.

Conclusions

The approval of new osteoporosis drugs and the establishment of osteoporosis liaison services have had a positive effect on the use of postoperative drug therapy in the orthopedic field. Our finding that the rate of secondary fracture within 1 year of the initial fracture remained around 2% every year, despite improvements in postoperative drug therapy, suggests that both rehabilitation for preventing falls and early postoperative drug therapy are essential to prevent secondary fractures.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Jacobsen SJ, Goldberg J, Miles TP, Brody JA, Stiers W, Rimm AA (1990) Hip fracture incidence among the old and very old: a population-based study of 745,435 cases. Am J Public Health 80:871–873

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Boonen S, Autier P, Barette M, Vanderschueren D, Lips P, Haentjens P (2004) Functional outcome and quality of life following hip fracture in elderly women: a prospective controlled study. Osteoporos Int 15:87–94. https://doi.org/10.1007/s00198-003-1515-z

    Article  PubMed  Google Scholar 

  3. Sambrook P, Cooper C (2006) Osteoporosis. Lancet 367:2010–2018. https://doi.org/10.1016/S0140-6736(06)68891-0

    Article  CAS  PubMed  Google Scholar 

  4. Dhanwal DK, Dennison EM, Harvey NC, Cooper C (2011) Epidemiology of hip fracture: Worldwide geographic variation. Indian J Orthop 45:15–22. https://doi.org/10.4103/0019-5413.73656

    Article  PubMed  PubMed Central  Google Scholar 

  5. Bhandari M, Swiontkowski M (2017) Management of acute hip fracture. N Engl J Med 377:2053–2062. https://doi.org/10.1056/NEJMcp1611090

    Article  PubMed  Google Scholar 

  6. Orimo H, Yaegashi Y, Onoda T, Fukushima Y, Hosoi T, Sakata K (2009) Hip fracture incidence in Japan: estimates of new patients in 2007 and 20-year trends. Arch Osteoporos 4:71–77. https://doi.org/10.1007/s11657-009-0031-y

    Article  PubMed  PubMed Central  Google Scholar 

  7. Orimo H, Yaegashi Y, Hosoi T, Fukushima Y, Onoda T, Hashimoto T, Sakata K (2016) Hip fracture incidence in Japan: Estimates of new patients in 2012 and 25-year trends. Osteoporos Int 27:1777–1784. https://doi.org/10.1007/s00198-015-3464-8

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Harada A, Matsui Y, Takemura M, Ito Z, Wakao N, Ota T (2005) Cost-utility analysis of osteoporosis. Nihon Ronen Igakkai Zasshi 42:596–608

    Article  PubMed  Google Scholar 

  9. Colon-Emeric C, Kuchibhatla M, Pieper C, Hawkes W, Fredman L, Magaziner J, Zimmerman S, Lyles KW (2003) The contribution of hip fracture to risk of subsequent fractures: data from two longitudinal studies. Osteoporos Int 14:879–883. https://doi.org/10.1007/s00198-003-1460-x

    Article  PubMed  Google Scholar 

  10. Hagino H, Sawaguchi T, Endo N, Ito Y, Nakano T, Watanabe Y (2012) The risk of a second hip fracture in patients after their first hip fracture. Calcif Tissue Int 90:14–21. https://doi.org/10.1007/s00223-011-9545-6

    Article  CAS  PubMed  Google Scholar 

  11. Yamanashi A, Yamazaki K, Kanamori M, Mochizuki K, Okamoto S, Koide Y, Kin K, Nagano A (2005) Assessment of risk factors for second hip fractures in Japanese elderly. Osteoporos Int 16:1239–1246. https://doi.org/10.1007/s00198-005-1835-2

    Article  PubMed  Google Scholar 

  12. Nymark T, Lauritsen JM, Ovesen O, Rock ND, Jeune B (2006) Short time-frame from first to second hip fracture in the Funen County Hip Fracture Study. Osteoporos Int 17:1353–1357. https://doi.org/10.1007/s00198-006-0125-y

    Article  CAS  PubMed  Google Scholar 

  13. Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, Cauley J, Black D, Vogt TM (1995) Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group. N Engl J Med 332:767–773. https://doi.org/10.1056/NEJM199503233321202

    Article  CAS  PubMed  Google Scholar 

  14. Gehlbach S, Saag KG, Adachi JD, Hooven FH, Flahive J et al (2012) Previous fractures at multiple sites increase the risk for subsequent fractures: the Global Longitudinal Study of Osteoporosis in Women. J Bone Miner Res 27:645–653. https://doi.org/10.1002/jbmr.1476

    Article  PubMed  Google Scholar 

  15. Solomon DH, Finkelstein JS, Katz JN, Mogun H, Avorn J (2003) Underuse of osteoporosis medications in elderly patients with fractures. Am J Med 115:398–400

    Article  PubMed  Google Scholar 

  16. Gardner MJ, Brophy RH, Demetrakopoulos D, Koob J, Hong R, Rana A, Lin JT, Lane JM (2005) Interventions to improve osteoporosis treatment following hip fracture. A prospective, randomized trial. J Bone Jt Surg Am 87:3–7. https://doi.org/10.2106/JBJS.D.02289

    Article  Google Scholar 

  17. Colon-Emeric CS, Lyles KW, House P, Levine DA, Schenck AP, Allison J, Gorospe J, Fermazin M, Oliver K, Curtis JR, Weissman N, Xie A, Saag KG (2007) Randomized trial to improve fracture prevention in nursing home residents. Am J Med 120:886–892. https://doi.org/10.1016/j.amjmed.2007.04.020

    Article  PubMed  PubMed Central  Google Scholar 

  18. Tsukutani Y, Hagino H, Ito Y, Nagashima H (2015) Epidemiology of fragility fractures in Sakaiminato, Japan: incidence, secular trends, and prognosis. Osteoporos Int 26:2249–2255. https://doi.org/10.1007/s00198-015-3124-z

    Article  CAS  PubMed  Google Scholar 

  19. McLellan AR, Gallacher SJ, Fraser M, McQuillian C (2003) The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture. Osteoporos Int 14:1028–1034. https://doi.org/10.1007/s00198-003-1507-z

    Article  PubMed  Google Scholar 

  20. Eisman JA, Bogoch ER, Dell R, Harrington JT, McKinney RE Jr, McLellan A, Mitchell PJ, Silverman S, Singleton R, Siris E, Prevention ATFoSF (2012) Making the first fracture the last fracture: ASBMR task force report on secondary fracture prevention. J Bone Miner Res 27:2039–2046. https://doi.org/10.1002/jbmr.1698

    Article  PubMed  Google Scholar 

  21. Hagino H, Endo N, Harada A, Iwamoto J, Mashiba T, Mori S, Ohtori S, Sakai A, Takada J, Yamamoto T (2017) Survey of hip fractures in Japan: recent trends in prevalence and treatment. J Orthop Sci 22:909–914. https://doi.org/10.1016/j.jos.2017.06.003

    Article  PubMed  Google Scholar 

  22. Iba K, Dohke T, Takada J, Sasaki K, Sonoda T, Hanaka M, Miyano S, Yamashita T (2018) Improvement in the rate of inadequate pharmaceutical treatment by orthopaedic surgeons for the prevention of a second fracture over the last 10 years. J Orthop Sci 23:127–131. https://doi.org/10.1016/j.jos.2017.09.008

    Article  PubMed  Google Scholar 

  23. Bogoch ER, Elliot-Gibson V, Beaton DE, Jamal SA, Josse RG, Murray TM (2006) Effective initiation of osteoporosis diagnosis and treatment for patients with a fragility fracture in an orthopaedic environment. J Bone Jt Surg Am 88:25–34. https://doi.org/10.2106/JBJS.E.00198

    Article  Google Scholar 

  24. Rozental TD, Makhni EC, Day CS, Bouxsein ML (2008) Improving evaluation and treatment for osteoporosis following distal radial fractures. A prospective randomized intervention. J Bone Jt Surg Am 90:953–961. https://doi.org/10.2106/JBJS.G.01121

    Article  Google Scholar 

  25. Miki RA, Oetgen ME, Kirk J, Insogna KL, Lindskog DM (2008) Orthopaedic management improves the rate of early osteoporosis treatment after hip fracture. A randomized clinical trial. J Bone Jt Surg Am 90:2346–2353. https://doi.org/10.2106/JBJS.G.01246

    Article  Google Scholar 

  26. Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF et al (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809. https://doi.org/10.1056/NEJMoa074941

    Article  CAS  PubMed  Google Scholar 

  27. Osaki M, Tatsuki K, Hashikawa T, Norimatsu T, Chiba K, Motokawa S, Furuichi I, Doiguchi Y, Aoyagi K, Shindo H (2012) Beneficial effect of risedronate for preventing recurrent hip fracture in the elderly Japanese women. Osteoporos Int 23:695–703. https://doi.org/10.1007/s00198-011-1556-7

    Article  CAS  PubMed  Google Scholar 

  28. Dretakis KE, Dretakis EK, Papakitsou EF, Psarakis S, Steriopoulos K (1998) Possible predisposing factors for the second hip fracture. Calcif Tissue Int 62:366–369

    Article  CAS  PubMed  Google Scholar 

  29. Wiktorowicz ME, Goeree R, Papaioannou A, Adachi JD, Papadimitropoulos E (2001) Economic implications of hip fracture: health service use, institutional care and cost in Canada. Osteoporos Int 12:271–278. https://doi.org/10.1007/s001980170116

    Article  CAS  PubMed  Google Scholar 

  30. Chapurlat RD, Bauer DC, Nevitt M, Stone K, Cummings SR (2003) Incidence and risk factors for a second hip fracture in elderly women. The study of osteoporotic fractures. Osteoporos Int 14:130–136. https://doi.org/10.1007/s00198-002-1327-6

    Article  CAS  PubMed  Google Scholar 

  31. Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY, Wong JB (2004) Effect of Vitamin D on falls: a meta-analysis. JAMA 291:1999–2006. https://doi.org/10.1001/jama.291.16.1999

    Article  CAS  PubMed  Google Scholar 

  32. van Helden S, Wyers CE, Dagnelie PC, van Dongen MC, Willems G, Brink PR, Geusens PP (2007) Risk of falling in patients with a recent fracture. BMC Musculoskelet Disord 8:55. https://doi.org/10.1186/1471-2474-8-55

    Article  PubMed  PubMed Central  Google Scholar 

  33. Johansson H, Siggeirsdottir K, Harvey NC, Oden A, Gudnason V, McCloskey E, Sigurdsson G, Kanis JA (2017) Imminent risk of fracture after fracture. Osteoporos Int 28:775–780. https://doi.org/10.1007/s00198-016-3868-0

    Article  CAS  PubMed  Google Scholar 

  34. Kanis JA, Johansson H, Oden A, Harvey NC, Gudnason V, Sanders KM, Sigurdsson G, Siggeirsdottir K, Fitzpatrick LA, Borgstrom F, McCloskey EV (2018) Characteristics of recurrent fractures. Osteoporos Int 29:1747–1757. https://doi.org/10.1007/s00198-018-4502-0

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

This project was supported in part by a Grant-in-Aid for Young Scientists (B) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan 17K16670 (T. Shimizu).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tomohiro Shimizu.

Ethics declarations

Conflict of interest

Shun Shimodan, Dai Sato, Kaname Takahashi, Ryosuke Hishimura, Masahiro Ota, Hirokazu Shimizu, Yuichi Hasegawa, Toshiya Chubachi, Takeru Tsujimoto, Yukinori Tsukuda, Tsuyoshi Asano, Daisuke Takahashi, Masahiko Takahata, Norimasa Iwasaki, Tomohiro Shimizu declare that they have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Shun Shimodan and Dai Sato are first authors.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Shimodan, S., Sato, D., Takahashi, K. et al. Ten years change in post-fracture care for hip fracture patients. J Bone Miner Metab 38, 222–229 (2020). https://doi.org/10.1007/s00774-019-01047-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00774-019-01047-3

Keywords

Navigation