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The Risk of a Second Hip Fracture in Patients after Their First Hip Fracture

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Abstract

We investigated the incidence of additional fractures and the rate of prescription of osteoporotic pharmacotherapy after an initial hip fracture. We surveyed female patients aged 65 and over who sustained their first hip fracture between January 1, 2006, and December 31, 2007, treated at 25 hospitals in five geographic areas in Japan. Data for 1 year after the first hip fracture were collected from medical records, and questionnaires were mailed to all patients. In total, 2,663 patients were enrolled, and 335 patients were excluded based on exclusion criteria. The analysis was performed on 2,328 patients. During the 1-year follow-up period 160 fractures occurred in 153 patients and 77 subsequent hip fractures occurred in 77 patients. The incidence of all additional fractures among patients who sustained their first hip fracture was 70 (per 1,000 person-year) and that for second hip fracture was 34. In comparison to the general population, women ≥65 years of age who sustained an initial hip fracture were four times as likely to sustain an additional hip fracture. Antiosteoporosis pharmacotherapy was prescribed for 436 patients (18.7%), while 1,240 patients (53.3%) did not receive any treatment during the 1-year period. Patients who have sustained one hip fracture have a higher risk of a second hip fracture compared to the general population, and most of these women receive no pharmaceutical treatment for osteoporosis.

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Acknowledgments

The authors sincerely acknowledge the staff members of the hospitals that cooperated with this Prevention of Second Hip Fracture (POSHIP) study. The authors also acknowledge the Japanese Society for Fracture Repair. The authors express their sincere appreciation to Ms. Kaoru Yamabe and Ms. Machiko Abe for their help in the analyses. The authors also acknowledge Ms. Ryoko Ikehara for her secretarial assistance. This study was mainly supported by a grant from the Japanese Society for Fracture Repair and partially supported by a grant-in-aid from the Ministry of Health, Labor and Welfare of Japan (21-shi, 23-22 Choujyu Iryou).

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Authors and Affiliations

  1. School of Health Science, Tottori University, 86 Nishi-Cho, Yonago, Tottori, 683-8503, Japan

    Hiroshi Hagino & Yasuyo Ito

  2. Department of Orthopedic Surgery, Toyama City Hospital, Toyama City, Japan

    Takeshi Sawaguchi

  3. Department of Orthopedic Surgery, Niigata University, Niigata, Japan

    Naoto Endo

  4. Department of Orthopedic Surgery, Tamana Central Hospital, Tamana, Japan

    Tetsuo Nakano

  5. Department of Orthopedic Surgery, Teikyo University, Tokyo, Japan

    Yoshinobu Watanabe

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  1. Hiroshi Hagino
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  2. Takeshi Sawaguchi
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  3. Naoto Endo
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  4. Yasuyo Ito
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  5. Tetsuo Nakano
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  6. Yoshinobu Watanabe
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Correspondence to Hiroshi Hagino.

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The authors have stated that they have no conflict of interest.

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Hagino, H., Sawaguchi, T., Endo, N. et al. The Risk of a Second Hip Fracture in Patients after Their First Hip Fracture. Calcif Tissue Int 90, 14–21 (2012). https://doi.org/10.1007/s00223-011-9545-6

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  • DOI: https://doi.org/10.1007/s00223-011-9545-6

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